Which term describes the inflammatory mediator released during the early phase of type 1 hypersensitivity response causing immediate bronchoconstriction and vasodilation?

Prostaglandins

Histamine

Leukotrienes

Bradykinin

Answer and Explanation

The Correct Answer is B

Choice A reason: Prostaglandins are inflammatory mediators that are derived from arachidonic acid. They are involved in both the early and late phases of type 1 hypersensitivity response, but they do not cause immediate bronchoconstriction and vasodilation. They mainly cause pain, fever, and inflammation.

Choice B reason: Histamine is an inflammatory mediator that is stored in mast cells and basophils. It is released during the early phase of type 1 hypersensitivity response, which occurs within minutes of exposure to an allergen. It causes immediate bronchoconstriction and vasodilation, as well as increased vascular permeability, mucus secretion, and itching.

Choice C reason: Leukotrienes are inflammatory mediators that are derived from arachidonic acid. They are involved in the late phase of type 1 hypersensitivity response, which occurs several hours after exposure to an allergen. They cause sustained bronchoconstriction and inflammation, as well as increased mucus production and airway edema.

Choice D reason: Bradykinin is an inflammatory mediator that is formed from plasma proteins. It is not directly involved in type 1 hypersensitivity response, but it may be activated by the complement system, which is part of the innate immune system. It causes vasodilation, increased vascular permeability, and pain.

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Correct Answer is B

Explanation

Choice A reason: Ischemia of the motor and sensory neurons in the brain is not the cause of multiple sclerosis, but a possible consequence of it. Ischemia is a lack of blood supply to the tissues, which may result from inflammation, thrombosis, or embolism. It may cause neuronal death, stroke, or dementia.

Choice B reason: Damage and scarring of the white matter in the brain is the best description of the cause of multiple sclerosis. Multiple sclerosis is an autoimmune disorder that causes the immune system to attack the myelin sheath, which is a protective layer that covers the nerve fibers. The damage and scarring of the myelin sheath, also called demyelination, disrupts the transmission of nerve impulses and causes various neurological symptoms.

Choice C reason: Infection of the parietal and temporal lobes of the brain is not the cause of multiple sclerosis, but a rare complication of it. Infection of the brain, also called encephalitis, may occur due to viral, bacterial, or fungal agents. It may cause fever, headache, confusion, seizures, or coma.

Choice D reason: Increased amounts of epinephrine and acetylcholine in the brain are not the cause of multiple sclerosis, but a possible effect of it. Epinephrine and acetylcholine are neurotransmitters that regulate the sympathetic and parasympathetic nervous systems, respectively. They may be affected by the demyelination of the nerve fibers, which may alter the autonomic functions such as heart rate, blood pressure, digestion, or bladder control.

A. Herpes simplex 2 virus B. Epstein-Barr virus C. Hepatitis C virus D. Rubella virus

Correct Answer is B

Explanation

Choice A reason: Herpes simplex 2 virus is not the microorganism that causes infectious mononucleosis, but a different type of herpes virus that causes genital herpes. Genital herpes is a sexually transmitted infection that causes painful blisters and ulcers in the genital area.

Choice B reason: Epstein-Barr virus is the best explanation for the microorganism that causes infectious mononucleosis. Epstein-Barr virus is a type of herpes virus that infects the B lymphocytes, which are a type of white blood cells. It causes infectious mononucleosis, also known as mono or the kissing disease, which is a common infection that causes fever, sore throat, swollen lymph nodes, and fatigue.

Choice C reason: Hepatitis C virus is not the microorganism that causes infectious mononucleosis, but a different type of virus that causes hepatitis C. Hepatitis C is a blood-borne infection that affects the liver. It causes inflammation, scarring, and cirrhosis of the liver, which may lead to liver failure or cancer.

Choice D reason: Rubella virus is not the microorganism that causes infectious mononucleosis, but a different type of virus that causes rubella. Rubella, also known as German measles, is a mild infection that causes a rash, fever, and swollen glands. It is preventable by vaccination and can be dangerous for pregnant women, as it may cause birth defects or miscarriage.

Viruses | Free Full-Text | Inflammation and Epstein–Barr Virus at the Crossroads of Multiple Sclerosis and Post-Acute Sequelae of COVID-19 Infection

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Which term describes the inflammatory mediator released during the early phase of type 1 hypersensitivity response causing immediate bronchoconstriction and vasodilation?

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