During assessment of a client diagnosed with severe anemia, the nurse notes pallor of the skin and mucous membranes. Which explanation is the best rationale for this finding?

Choice A reason: Glomerulonephritis is an inflammation of the glomeruli, the filtering units of the kidneys. It can cause damage to the renal tissue and lead to intrinsic acute kidney injury, not prerenal acute kidney injury.

Choice B reason: Fluid volume deficit is a condition in which the body loses more fluid than it takes in. It can cause hypovolemia, which reduces the blood flow to the kidneys and impairs their function. This is the most common cause of prerenal acute kidney injury, which is a result of decreased perfusion to the kidneys.

Choice C reason: Neurogenic bladder is a dysfunction of the bladder caused by a nerve problem. It can affect the ability to store or empty urine. It can cause urinary retention, which increases the pressure in the urinary tract and damages the kidneys. This is a type of postrenal acute kidney injury, which is a result of obstruction to the urine outflow.

Choice D reason: Renal calculus is a solid mass formed from crystals in the urine. It can block the ureter, the tube that carries urine from the kidney to the bladder. It can cause hydronephrosis, which is a swelling of the kidney due to accumulation of urine. This is another type of postrenal acute kidney injury.

Choice A reason: Muscle weakness and motor seizures are not the most serious complication because they are signs of electrolyte imbalance, not urinary tract infection. Electrolyte imbalance is a condition where the levels of minerals and salts in the blood are too high or too low, which can affect the nerve and muscle function, causing symptoms such as weakness, spasms, or seizures. Electrolyte imbalance can be caused by various factors, such as dehydration, kidney failure, or medications.

Choice B reason: Upper abdominal pain and cramping are not the most serious complication because they are signs of gastritis, not urinary tract infection. Gastritis is a condition where the lining of the stomach is inflamed, causing symptoms such as pain, nausea, or vomiting. Gastritis can be caused by various factors, such as infections, stress, or medications.

Choice C reason: Confusion and agitation are the most serious complication because they are signs of sepsis, which is a life-threatening condition where the body's response to an infection causes widespread inflammation and organ damage. Sepsis can be caused by various types of infections, including urinary tract infection, which is an infection that affects the bladder, urethra, or kidneys. Sepsis can cause symptoms such as confusion, agitation, fever, chills, or shock.

Choice D reason: Periorbital edema and cardiac dysrhythmias are not the most serious complication because they are signs of heart failure, not urinary tract infection. Heart failure is a condition where the heart cannot pump enough blood to meet the body's needs, causing symptoms such as swelling, shortness of breath, or irregular heartbeat. Heart failure can be caused by various factors, such as coronary artery disease, hypertension, or diabetes.