Which statement is correct about patient tolerance to medications?
The patient will continually require higher doses of the drug for the same effect to be achieved.
Tolerance occurs when the liver or kidneys are no longer able to metabolize the drug.
The patient will require a stable dose of the medication until the drug is discontinued.
Tolerance only develops when the patients do not take the medication as it is prescribed.
The Correct Answer is A
Choice A reason: Tolerance reflects receptor desensitization or enzyme induction; higher doses compensate for reduced drug efficacy, a common pharmacological adaptation.
Choice B reason: Organ failure affects metabolism, not tolerance; tolerance is a cellular response, not solely a failure of liver or kidney drug clearance mechanisms.
Choice C reason: Stable dosing contradicts tolerance; if tolerance develops, efficacy drops, necessitating dose increases, not maintenance, to achieve therapeutic levels.
Choice D reason: Non-adherence may alter response, but tolerance occurs with consistent use; it’s a physiological adaptation, not a result of misuse or skipping doses.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A reason: Lisinopril is Zestril’s generic name; an ACE inhibitor, it’s widely used for hypertension, matching the context of a common medication order.
Choice B reason: Acetaminophen, a pain reliever, isn’t Zestril’s generic; it lacks antihypertensive action, making it irrelevant to the implied medication class.
Choice C reason: Morphine, an opioid, treats pain, not hypertension; it doesn’t align with Zestril’s purpose or class, ruling it out as the generic name.
Choice D reason: Fentanyl, another opioid, addresses pain, not blood pressure; it’s unrelated to Zestril’s therapeutic role, excluding it from consideration.
Correct Answer is B
Explanation
Choice A reason: A 12-degree angle is too shallow, increasing the risk of incorrect placement and ineffective administration of the intradermal injection.
Choice B reason: The 15-degree angle ensures precise intradermal placement, forming a wheal that indicates proper administration into the dermis for optimal absorption.
Choice C reason: A 30-degree angle places the medication too deep into subcutaneous tissue, compromising intended drug absorption.
Choice D reason: A 45-degree angle results in subcutaneous rather than intradermal injection, altering the drug’s effectiveness and purpose.
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