Which of the following statements best describes the effect of hyposecretion of antidiuretic hormone (ADH) on urine output?
Urine output increases and becomes concentrated.
Urine output increases and becomes dilute.
Urine output decreases and becomes concentrated.
Urine output decreases and becomes dilute.
The Correct Answer is B
In diabetes insipidus, the hyposecretion of antidiuretic hormone (ADH) leads to decreased water reabsorption in the kidneys, resulting in increased urine output. The urine produced is dilute and lacks the normal concentration of solutes.
Incorrect choices:
a. This choice is incorrect. Urine output increases, but it becomes dilute, not concentrated.
c. This choice is incorrect. Urine output increases, and the urine becomes dilute, not concentrated.
d. This choice is incorrect. Urine output increases, but it becomes dilute, not concentrated.
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Correct Answer is C
Explanation
Central diabetes insipidus (CDI) can be caused by trauma or injury to the hypothalamus or pituitary gland, which disrupts the production or release of antidiuretic hormone (ADH). Other causes of CDI include tumors, infections, and certain medications.
Incorrect choices:
a. This choice is incorrect. Excessive fluid intake can lead to increased urine output, but it is not a cause of CDI.
b. This choice is incorrect. Kidney dysfunction is not a common cause of central diabetes insipidus.
d. This choice is incorrect. Hypersecretion of aldosterone would lead to sodium retention and increased fluid volume, which is not characteristic of central diabetes insipidus.
Correct Answer is D
Explanation
Excessive fluid intake to compensate for fluid loss in diabetes insipidus (DI) can lead to weight loss as the body attempts to excrete excess water.
Incorrect choices:
a. This choice is incorrect. Bradycardia is not typically associated with excessive fluid intake or diabetes insipidus.
b. This choice is incorrect. Hypotension is not typically associated with excessive fluid intake or diabetes insipidus.
c. This choice is incorrect. Edema is not typically associated with excessive fluid intake or diabetes insipidus.
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