Which cytotoxic lymphocyte granules contain serine proteases that induce apoptosis in target cells?
Perforins.
Cytokines.
Granzymes.
Interferons.
The Correct Answer is C
Granzymes are a family of serine proteases that are stored in and secreted from the cytotoxic granules of cytotoxic T lymphocytes (CTL) and natural killer (NK) cells.
They work in synergy with perforin, a pore-forming toxin, to induce apoptosis in target cells.
Perforin is necessary for the delivery of granzyme B to the target cell cytosol where caspase-dependent and -independent pathways to apoptosis are activated.
Perforins (choice A) are pore-forming toxins that work in synergy with granzymes to induce apoptosis in target cells.
Cytokines (choice B) are signaling molecules that regulate immune responses but do not directly induce apoptosis in target cells.
Interferons (choice D) are a type of cytokine that play a role in immune responses but do not directly induce apoptosis in target cells.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Bacteria can perform photosynthesis while archaea cannot. Many types of bacteria can generate oxygen from sunlight through photosynthesis, while archaea cannot perform this process.
Choice A is incorrect because neither bacteria nor archaea have a true nucleus. Both are prokaryotic organisms.
Choice B is incorrect because archaea reproduce by fission, fragmentation, or budding, while bacteria can produce spores and divide sexually or asexually. Choice D is incorrect because archaeal and bacterial flagella are constructed differently.
Correct Answer is B
Explanation
Carbon monoxide binds to the haemoglobin to create a molecule called carboxyhemoglobin (COHb), which interferes with the body’s ability to transport and use oxygen, especially in the brain.
Choice A is incorrect because carbon monoxide poisoning occurs when carbon monoxide builds up in your bloodstream.
Choice C is incorrect because carbon monoxide poisoning does not increase the production of red blood cells.
Choice D is incorrect because decreased pulmonary function is not a potential complication of carbon monoxide poisoning.
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