Which cytotoxic lymphocyte granules contain serine proteases that induce apoptosis in target cells?
Perforins.
Cytokines.
Granzymes.
Interferons.
The Correct Answer is C
Granzymes are a family of serine proteases that are stored in and secreted from the cytotoxic granules of cytotoxic T lymphocytes (CTL) and natural killer (NK) cells.
They work in synergy with perforin, a pore-forming toxin, to induce apoptosis in target cells.
Perforin is necessary for the delivery of granzyme B to the target cell cytosol where caspase-dependent and -independent pathways to apoptosis are activated.
Perforins (choice A) are pore-forming toxins that work in synergy with granzymes to induce apoptosis in target cells.
Cytokines (choice B) are signaling molecules that regulate immune responses but do not directly induce apoptosis in target cells.
Interferons (choice D) are a type of cytokine that play a role in immune responses but do not directly induce apoptosis in target cells.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
The plasma membrane is the organelle that encapsulates the contents of the cell and plays a vital role in regulating the movement of substances in and out of the cell.
It is a selectively permeable barrier that separates the internal environment of the cell from the external environment.
Choice A is incorrect because ribosomes are organelles involved in protein synthesis, not in regulating the movement of substances in and out of the cell.
Choice B is incorrect because the nucleus is an organelle that contains the cell’s genetic material, not in regulating the movement of substances in and out of the cell.
Choice C is incorrect because mitochondria are organelles involved in energy production, not in regulating the movement of substances in and out of the cell.
Correct Answer is B
Explanation
A catalyst provides a new reaction pathway in which a lower activation energy is offered.
This allows more reactant molecules to collide with enough energy to surmount the smaller energy barrier, increasing the rate of reaction 2.
Choice A, It increases the activation energy required for the reaction, is not the correct answer because it describes the opposite effect of a catalyst.
Choice C, It has no effect on the activation energy required for the reaction, is not the correct answer because a catalyst does have an effect on activation energy.
Choice D, It increases the rate of reaction but has no effect on the activation energy, is not the correct answer because a catalyst increases the rate of reaction by decreasing the activation energy.
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