What instruction for oral administration of methotrexate should the nurse include when teaching a client diagnosed with rheumatoid arthritis?
Use an antiemetic one hour following administration.
Drink 2-3 liters of water per day.
Rinse mouth twice per day with an alcohol-based mouthwash.
Take the medication with an NSAID.
The Correct Answer is D
Choice A Reason
Using an antiemetic one hour after administration of methotrexate is not a standard recommendation. Antiemetics are typically used to prevent nausea and vomiting associated with chemotherapy and are taken before or at the time of methotrexate administration, not afterward.
Choice B Reason
Drinking 2-3 liters of water per day is important for patients taking methotrexate to prevent kidney damage by ensuring adequate hydration and facilitating the excretion of the drug¹. Methotrexate can be nephrotoxic, and proper hydration helps to mitigate this risk.
Choice C Reason
Rinsing the mouth with an alcohol-based mouthwash is not recommended for patients taking methotrexate. Alcohol can cause drying and irritation, which might exacerbate any mouth sores caused by methotrexate. Instead, patients should use a gentle, non-alcoholic mouthwash to maintain oral hygiene.
Choice D Reason
Taking methotrexate with an NSAID is not advised without specific medical guidance. NSAIDs can increase the toxicity of methotrexate by displacing it from protein-binding sites and reducing its renal clearance, potentially leading to increased side effects.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A reason:
While polyhydramnios can be associated with congenital anomalies or fetal distress, it is not a direct indication of these conditions. Polyhydramnios refers specifically to the excessive accumulation of amniotic fluid. Congenital anomalies may lead to polyhydramnios if they affect the fetus's ability to swallow and process amniotic fluid normally, but the presence of polyhydramnios alone does not confirm these conditions.
Choice B reason:
Elevated levels of alpha-fetoprotein (AFP) in the amniotic fluid can be indicative of neural tube defects or other fetal abnormalities, but they are not a defining characteristic of polyhydramnios. Normal AFP levels in amniotic fluid at 15 to 21 weeks' gestation range from 10 to 150 ng/ml. Polyhydramnios is diagnosed based on the volume of amniotic fluid, not the AFP levels.
Choice C reason:
Carrying more than one fetus can lead to an increased amount of amniotic fluid, potentially resulting in polyhydramnios. However, the diagnosis of polyhydramnios itself does not imply a multiple gestation pregnancy. It simply indicates that there is more amniotic fluid than usual.
Choice D reason:
Polyhydramnios is defined as an excessive amount of amniotic fluid. It is typically diagnosed when the amniotic fluid index (AFI) exceeds 24 cm or the single deepest pocket (SDP) measures more than 8 cm. This condition can occur due to various reasons, including fetal anomalies, maternal diabetes, and other medical conditions.

Correct Answer is ["A","C","D"]
Explanation
Choice a reason:
Avoiding crossing the legs while sitting is crucial after a total hip replacement to prevent dislocation of the new joint. Crossing the legs can put undue pressure on the hip joint and may lead to misalignment or increased strain during the healing process.
Choice b reason:
Eliminating Vitamin K from the diet is not typically recommended after a total hip replacement. Vitamin K is essential for blood clotting, and maintaining a consistent intake is important, especially if the client is on anticoagulant therapy to prevent deep vein thrombosis. Sudden changes in Vitamin K intake can affect the efficacy of anticoagulants like warfarin.
Choice c reason:
Following a home exercise program is an essential part of recovery after a total hip replacement. Exercises help strengthen the muscles around the new joint, improve flexibility, and increase range of motion. It's important that these exercises are done regularly and as instructed by a physical therapist.
Choice d reason:
Using a raised toilet seat after hip replacement surgery helps to prevent excessive flexion at the hip, which can risk dislocating the new joint. It also makes it easier for the client to sit down and stand up with less strain on the hip.
Choice e reason:
Increasing high-impact activities is not recommended after a total hip replacement, especially in the early stages of recovery. High-impact activities can put excessive stress on the new joint and may lead to complications. Low-impact activities such as walking, swimming, or cycling are generally more appropriate.
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