What instruction for oral administration of methotrexate should the nurse include when teaching a client diagnosed with rheumatoid arthritis?
Use an antiemetic one hour following administration.
Drink 2-3 liters of water per day.
Rinse mouth twice per day with an alcohol-based mouthwash.
Take the medication with an NSAID.
The Correct Answer is D
Choice A Reason
Using an antiemetic one hour after administration of methotrexate is not a standard recommendation. Antiemetics are typically used to prevent nausea and vomiting associated with chemotherapy and are taken before or at the time of methotrexate administration, not afterward.
Choice B Reason
Drinking 2-3 liters of water per day is important for patients taking methotrexate to prevent kidney damage by ensuring adequate hydration and facilitating the excretion of the drug¹. Methotrexate can be nephrotoxic, and proper hydration helps to mitigate this risk.
Choice C Reason
Rinsing the mouth with an alcohol-based mouthwash is not recommended for patients taking methotrexate. Alcohol can cause drying and irritation, which might exacerbate any mouth sores caused by methotrexate. Instead, patients should use a gentle, non-alcoholic mouthwash to maintain oral hygiene.
Choice D Reason
Taking methotrexate with an NSAID is not advised without specific medical guidance. NSAIDs can increase the toxicity of methotrexate by displacing it from protein-binding sites and reducing its renal clearance, potentially leading to increased side effects.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A Reason:
Avoiding frustration by performing activities of daily living (ADLs) for the client may seem helpful, but it can actually lead to increased dependency and a faster decline in the ability to perform these tasks. It is important to encourage independence as much as possible.
Choice B Reason:
Telling jokes or riddles and discussing new items might provide temporary entertainment but does not necessarily help a client with dementia function better in their environment. It could also potentially cause confusion or frustration if the client does not understand or remember the context.
Choice C Reason:
Bringing new topics and options to the client's attention can be overwhelming and may contribute to confusion. Clients with dementia benefit from consistency and routine, which helps them feel more secure and oriented.
Choice D Reason:
Assisting the client to perform simple tasks by giving step-by-step directions is a beneficial intervention. It supports the client's ability to maintain independence and function within their environment for as long as possible. This approach aligns with the goal of maximizing the client's abilities and fostering a sense of accomplishment.
Correct Answer is B
Explanation
Choice A Reason
An oral temperature of 100.6°F may indicate that the client still has a fever, which could suggest ongoing infection. However, temperature alone is not the most reliable indicator of the effectiveness of antibiotic therapy, as it can be influenced by various factors.
Choice B Reason
Pulse oximetry measures the oxygen saturation of the blood, which is a direct indicator of respiratory function. For a client with pneumonia, an improvement in oxygen saturation to 98% on room air is a strong sign that the lungs are effectively exchanging gases and that the pneumonia is resolving. This would be a clear indication that the amoxicillin is effective.
Choice C Reason
An increased neutrophil count is a sign of acute infection, but it does not directly measure the effectiveness of the antibiotic therapy. Neutrophil counts can remain elevated even as the infection is resolving, so they are not the best sole indicator of therapeutic effectiveness.
Choice D Reason
Adequate urine output is important for overall health and indicates good kidney function, but it is not a direct measure of the effectiveness of antibiotic therapy for pneumonia. Urine output does not reflect the respiratory status or the resolution of lung infection.
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