What factors affect physiological response to drug use?
Age, weight, and sex
Marital status and family history.
Diet and exercise
Socioeconomic status and education level
The Correct Answer is A
A) Age, weight, and sex:
Age, weight, and sex are key factors that significantly affect an individual's physiological response to drug use. These factors influence how the body absorbs, distributes, metabolizes, and excretes medications. For example, older adults may have slower metabolism and decreased renal function, requiring dosage adjustments. Body weight can affect the distribution of drugs, with heavier individuals potentially requiring higher doses for the same therapeutic effect. Sex also plays a role, as men and women can have differences in drug absorption and metabolism due to hormonal and physiological variations.
B) Marital status and family history:
Marital status and family history do not directly affect the physiological response to medications in the way that biological factors like age, weight, and sex do. While family history may provide insights into genetic predispositions for certain diseases, it does not significantly impact the pharmacodynamics of most medications. Marital status is largely a social factor and does not influence drug metabolism or effects.
C) Diet and exercise:
Diet and exercise can influence drug absorption and metabolism to some extent, but they are not as direct or universal in their impact as factors like age, weight, and sex. For example, high-fat meals can delay the absorption of certain medications, and exercise can affect the metabolism of some drugs. However, these are secondary factors compared to biological characteristics such as age and weight that directly alter how the body processes drugs.
D) Socioeconomic status and education level:
While socioeconomic status and education level can influence medication adherence and access to healthcare, they do not directly affect the body's physiological response to drugs. These factors may affect how a patient manages their health or accesses medical care, but they do not influence the pharmacokinetics or pharmacodynamics of drugs in the body.
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Related Questions
Correct Answer is B
Explanation
A) There is an increased risk of hyperthyroidism:
High levels of LDL cholesterol are not associated with hyperthyroidism. Hyperthyroidism is a condition related to an overactive thyroid gland, which affects metabolism and hormone levels but does not directly impact LDL cholesterol levels.
B) There is an increased risk of heart disease:
LDL cholesterol, often referred to as "bad cholesterol," contributes to the buildup of fatty plaques in the walls of arteries, a process known as atherosclerosis. This buildup can narrow and harden the arteries, leading to reduced blood flow and increasing the risk of heart disease, including conditions such as coronary artery disease, heart attack, and stroke. High LDL levels are considered one of the most significant modifiable risk factors for cardiovascular disease.
C) There is the possibility of digestive problems:
While very high cholesterol levels can sometimes contribute to the formation of gallstones, high LDL cholesterol levels are not directly linked to digestive problems. The primary concern with high LDL is its contribution to cardiovascular disease rather than digestive health.
D) There is an increased risk of rhabdomyolysis:
Rhabdomyolysis is a condition caused by the breakdown of muscle tissue, which can lead to the release of muscle proteins into the bloodstream. While certain medications used to lower cholesterol, such as statins, can cause muscle pain and, in rare cases, lead to rhabdomyolysis, high LDL itself is not a direct cause of rhabdomyolysis. The main health concern with high LDL is its contribution to heart disease.
Correct Answer is D
Explanation
A) Nausea
Nausea is not the most common or primary complication associated with thrombolytic drugs. While some patients may experience nausea as a minor side effect, it is not the hallmark complication of thrombolytic therapy. Thrombolytic drugs are used to dissolve blood clots, and their primary concern is related to bleeding due to their potent effect on clotting factors.
B) Hypertension
Hypertension (high blood pressure) is not typically associated with thrombolytic therapy. In fact, thrombolytic drugs are more likely to cause hypotension (low blood pressure) in some cases, especially if bleeding complications lead to significant blood loss.
C) Fever
Fever can occur as a side effect of many medications or conditions, but it is not a common or direct complication of thrombolytic therapy. Fever may occasionally arise as a response to infection, inflammation, or even the breakdown of clots, but it is not a primary concern when using thrombolytic drugs.
D) Bleeding
Bleeding is the most common and serious complication associated with thrombolytic drugs. These medications work by breaking down fibrin, the protein responsible for clot formation, to dissolve blood clots. While this is beneficial in conditions like myocardial infarction, stroke, or pulmonary embolism, it increases the risk of bleeding throughout the body. Bleeding can occur at various sites, including internal bleeding, gastrointestinal bleeding, and bleeding at the injection site.
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