Vomiting of stomach contents or continuous nasogastric suctioning may predispose to the development of:

Choice A Reason:

Inducer medications do not increase the blood level of newly added medications. Instead, they enhance the activity of enzymes that metabolize drugs, leading to a faster breakdown and lower concentration of the new medication in the bloodstream. This can result in reduced efficacy of the newly added medication.

Choice B Reason:

Inducer medications increase the activity of enzymes, particularly those in the cytochrome P450 family, which are responsible for drug metabolism. This increased enzyme activity accelerates the breakdown of the newly added medication, thereby decreasing its blood level and potentially reducing its therapeutic effect. For example, rifampin is a well-known inducer that can significantly lower the levels of drugs metabolized by CYP3A4.

Choice C Reason:

Inducer medications do not increase the half-life of newly added medications. On the contrary, by enhancing the metabolic activity of enzymes, they typically reduce the half-life of the new medication. This means the drug is broken down and eliminated from the body more quickly.

Choice D Reason:

Inducer medications do have a significant effect on new medications. They alter the metabolism of drugs by increasing the activity of metabolic enzymes, which can lead to decreased blood levels and reduced effectiveness of the new medication. Ignoring this interaction can result in subtherapeutic drug levels and treatment failure.

Choice A Reason:

The exhaustion stage is the final phase of the general adaptation syndrome (GAS). It occurs when the body has been exposed to stress for a prolonged period and can no longer maintain resistance. Symptoms of exhaustion include fatigue, burnout, depression, and decreased stress tolerance. Since the student is experiencing an immediate response to a sudden stressor, this stage does not apply.

Choice B Reason:

Adaptation is not a specific stage in the general adaptation syndrome. The correct stages are alarm, resistance, and exhaustion. Therefore, this choice is incorrect.

Choice C Reason:

This is the correct answer. The alarm stage is the initial phase of the general adaptation syndrome, also known as the “fight-or-flight” response. During this stage, the body reacts to a stressor by activating the sympathetic nervous system, which leads to increased heart rate, rapid breathing, and heightened alertness. The student’s reaction to the near-miss accident fits this description perfectly.

Choice D Reason:

The stage of resistance is the second phase of the general adaptation syndrome. During this stage, the body attempts to adapt to the stressor and return to a state of balance. If the stressor persists, the body remains on high alert, but the initial shock of the alarm stage has passed. Since the student’s response is immediate and acute, it aligns with the alarm stage rather than the resistance stage.