The nurse provides care for a client with a 10-year history of Crohn's disease. Which finding best describes a common complication of Crohn's disease?

Choice A reason: Initiates the fibrinolytic process in the arteries is not a role of inflammation in the development of atherosclerosis, but a protective mechanism against it. Fibrinolysis is the breakdown of blood clots by enzymes such as plasmin. It prevents the formation of thrombi that can occlude the arteries and cause ischemia.

Choice B reason: Decreases highly sensitive C-reactive protein (hsCRP) levels is not a role of inflammation in the development of atherosclerosis, but an indicator of it. hsCRP is a marker of systemic inflammation that is produced by the liver in response to cytokines. It is elevated in patients with atherosclerosis and correlates with the risk of cardiovascular events.

Choice C reason: Damages the endothelium of the arteries is the main role of inflammation in the development of atherosclerosis. Endothelial injury exposes the subendothelial layer to the blood, which triggers the adhesion of monocytes and platelets. Monocytes differentiate into macrophages and engulf oxidized low-density lipoproteins (LDL), forming foam cells. Foam cells accumulate in the intima and form fatty streaks, which are the earliest lesions of atherosclerosis.

Choice D reason: Causes diffuse arterial vasoconstriction is not a role of inflammation in the development of atherosclerosis, but a consequence of it. Atherosclerosis narrows the lumen of the arteries and reduces the blood flow to the tissues. This causes ischemia, which stimulates the release of vasoconstrictors such as angiotensin II and endothelin. Vasoconstriction further worsens the ischemia and increases the blood pressure.

Choice A reason: "Are you experiencing any nausea at this time?" is not the highest priority question because it is a common side effect of anesthesia, which is usually given during a thyroidectomy. Nausea is not a life-threatening complication, and it usually resolves within a few days after surgery.

Choice B reason: "Have you noticed any decrease in muscle weakness?" is not the highest priority question because it is a sign of improvement in the client's condition. A subtotal thyroidectomy is a surgical procedure that removes part of the thyroid gland, which is responsible for producing hormones that regulate the metabolism, growth, and development of the body. A client who has a thyroidectomy may have hypothyroidism, which is a condition where the thyroid gland does not produce enough hormones, causing symptoms such as fatigue, weight gain, and muscle weakness. A decrease in muscle weakness indicates that the client is responding well to the hormone replacement therapy, which is usually given after a thyroidectomy.

Choice C reason: "Do you have any numbness or tingling of your hands?" is the highest priority question because it is a sign of a possible complication of a thyroidectomy, which is hypocalcemia. Hypocalcemia is a condition where the blood has a low level of calcium, which is an electrolyte that helps regulate the nerve and muscle function, including the heart. A thyroidectomy can cause hypocalcemia if the parathyroid glands, which are small glands that are located behind the thyroid gland and produce a hormone that regulates the calcium level in the blood, are accidentally damaged or removed during the surgery. Hypocalcemia can cause symptoms such as numbness and tingling of the hands, feet, and lips, muscle spasms, seizures, and cardiac arrhythmias, which can be fatal if not treated promptly.

Choice D reason: "Do you have any breathing difficulties while walking?" is not the highest priority question because it is a sign of a possible complication of a thyroidectomy, which is tracheal compression. Tracheal compression is a condition where the trachea, which is the airway that connects the mouth and nose to the lungs, is squeezed or narrowed by the swelling or bleeding of the tissues around the thyroid gland. Tracheal compression can cause symptoms such as difficulty breathing, hoarseness, stridor, and cyanosis, which can be life-threatening if not treated promptly. However, tracheal compression is more likely to occur immediately after surgery, not 48 hours later.