The nurse is preparing to administer Reglan to a patient. She is most concerned by the following information in the patient's medical record?

Past medical history of benign prostatic hyperplasia (BPH)

Blood pressure of 132/82

Allergy to corn

Past medical history of gout

Answer and Explanation

The Correct Answer is C

Choice A reason: Past medical history of benign prostatic hyperplasia (BPH) is not a contraindication or a concern for administering Reglan, which is a medication that stimulates the motility of the upper gastrointestinal tract and treats nausea, heartburn, and gastroparesis¹. Reglan does not affect the prostate or urinary function.

Choice B reason: Blood pressure of 132/82 is slightly above the normal range of 120/80, but it is not a cause for concern or a reason to withhold Reglan. Reglan can lower the blood pressure by reducing the fluid volume and preventing sodium retention¹. The nurse should monitor the blood pressure regularly, but does not need to notify the health care provider about this finding.

Choice C reason: Allergy to corn is a concern for administering Reglan, as some formulations of Reglan may contain corn starch as an inactive ingredient. Corn starch can trigger an allergic reaction in people who are sensitive to corn, causing symptoms such as rash, itching, swelling, or anaphylaxis. The nurse should check the label of the Reglan product and avoid using it if it contains corn starch. The nurse should also notify the health care provider and the pharmacy about the patient's allergy and request an alternative medication or formulation.

Choice D reason: Past medical history of gout is not a contraindication or a concern for administering Reglan, which is a medication that stimulates the motility of the upper gastrointestinal tract and treats nausea, heartburn, and gastroparesis¹. Reglan does not affect the uric acid levels or the joints.

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Correct Answer is B

Explanation

Choice A reason: This is incorrect. Lisinopril is an angiotensin converting enzyme (ACE) inhibitor that lowers blood pressure and reduces the workload of the heart. It does not have a diuretic effect, meaning it does not increase urination.
Choice B reason: This is correct. Lisinopril can cause orthostatic hypotension, which is a sudden drop in blood pressure when changing positions. This can lead to dizziness, fainting, or falls. To prevent this, the nurse should instruct the client to rise slowly from sitting or lying positions and to avoid sudden movements.
Choice C reason: This is incorrect. Lisinopril can be taken with or without food. Taking it on an empty stomach does not improve its effectiveness or reduce its side effects.
Choice D reason: This is incorrect. Lisinopril does not cause weight gain due to fluid retention. In fact, it can help reduce edema, which is swelling caused by excess fluid in the body.

A. Antibiotics B. Pharmacologic Drug C. Prototype Drug D. Therapeutic Drug

Correct Answer is C

Explanation

Choice A reason: This is incorrect. Antibiotics are not a term for a drug model, but a class of drugs that are used to treat bacterial infections. Antibiotics can have different chemical structures, mechanisms of action, and modes of action. For example, penicillin is a prototype drug of the beta lactam antibiotics, which inhibit the synthesis of bacterial cell walls¹.

Choice B reason: This is incorrect. Pharmacologic drug is not a term for a drug model, but a general term for any substance that has a physiological effect on the body. Pharmacologic drugs can belong to different classes, such as analgesics, antihistamines, or antivirals. For example, aspirin is a prototype drug of the nonsteroidal anti-inflammatory drugs (NSAIDs), which reduce pain, inflammation, and fever.

Choice C reason: This is correct. Prototype drug is the term used for a well understood drug model with which other drugs in its representative class are compared. A prototype drug is an individual drug that has similar chemical structure, mechanism of action, and mode of action as other drugs in its class. A prototype drug is often the first developed or the most important drug in its class, and is used as a reference for comparison. For example, morphine is a prototype drug of the opioid analgesics, which relieve pain by binding to opioid receptors in the brain and spinal cord.

Choice D reason: This is incorrect. Therapeutic drug is not a term for a drug model, but a term for any drug that is used to treat or prevent a disease or disorder. Therapeutic drugs can belong to different classes, such as antibiotics, antihypertensives, or antidepressants. For example, metformin is a prototype drug of the biguanide antidiabetic drugs, which lower blood glucose levels by reducing glucose production in the liver and increasing glucose uptake in the muscles.

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The nurse is preparing to administer Reglan to a patient. She is most concerned by the following information in the patient's medical record?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Which of the following instructions should a nurse give to a client who is starting lisinopril?

Correct Answer is B

Explanation

What is the term used for a well understood drug model with which other drugs in its representative class are compared?

Correct Answer is C

Explanation

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What does the term 'first pass effect' refer to?

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