The nurse is preparing to administer a prescription for cefazolin 600 mg IM every six hours. The available vial is labeled, *Cefazolin 1 gram," and the instructions for reconstitution state, "For IM use add 2 mL sterile water for injection. Total volume reconstitution equals 2.5 mL." When reconstituted, how many milligrams are in each mL of solution? (Enter numeric value only)
The Correct Answer is ["400"]
Given:
Vial strength: Cefazolin 1 gram (1000 mg)
Volume of diluent: 2 mL sterile water
Total volume after reconstitution: 2.5 mL
Step 1: Calculate the concentration of Cefazolin in the reconstituted solution:
Concentration (mg/mL) = Total amount of Cefazolin (mg) / Total volume of solution (mL)
Concentration (mg/mL) = 1000 mg / 2.5 mL
Concentration (mg/mL) = 400 mg/mL
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["60"]
Explanation
Given:
Ordered dose: 25 mL PO every 6 hours PRN
Medication label: "Acetaminophen and Codeine Phosphate Oral Solution, USP: 120/12 mg per 5 mL"
Step 1: Determine the concentration of codeine in the solution:
Concentration of Codeine = Amount of Codeine / Volume of Solution
Concentration of Codeine = 12 mg / 5 mL
Concentration of Codeine = 2.4 mg/mL
Step 2: Calculate the amount of codeine per dose:
Amount of Codeine per Dose = Concentration of Codeine x Volume per Dose
Amount of Codeine per Dose = 2.4 mg/mL x 25 mL
Amount of Codeine per Dose = 60 mg
Correct Answer is ["42"]
Explanation
Given:
Volume of fluid: 1 liter = 1000 mL
Infusion time: 8 hours
Drop factor: 20 gtt/mL
Formula:
Flow rate (gtt/min) = (Volume (mL) / Time (hr)) x Drop factor (gtt/mL) / 60 min/hr
Step 1: Calculate the infusion rate in mL/hr:
Infusion rate (mL/hr) = Volume (mL) / Time (hr)
Infusion rate (mL/hr) = 1000 mL / 8 hr
Infusion rate (mL/hr) = 125 mL/hr
Step 2: Calculate the flow rate in gtt/min:
Flow rate (gtt/min) = (Infusion rate (mL/hr) x Drop factor (gtt/mL)) / 60 min/hr
Flow rate (gtt/min) = (125 mL/hr x 20 gtt/mL) / 60 min/hr
Flow rate (gtt/min) = 2500 gtt/hr / 60 min/hr
Flow rate (gtt/min) = 41.667 gtt/min
Step 3: Round to the nearest whole number:
Flow rate (gtt/min) ≈ 42 gtt/min
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