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The healthcare provider prescribes interferon beta-1b 0.0625 mg SUBQ every other day for a client with multiple sclerosis. The nurse reconstitutes the single-use vial of powder labeled, "0.3 mg with 1.2 mL of sterile water." How many mL should the nurse administer to the client? (Enter the numerical value only. If rounding is required, round to the nearest hundredth.)
Answer and Explanation

The Correct Answer is ["0.25"]

Here's how to calculate the volume the nurse should administer after reconstituting the medication:

Reconstitution:

The medication vial is labeled "0.3 mg with 1.2 mL of sterile water." This means adding 1.2 mL of diluent will result in a total volume of 1.2 mL solution.

 

Important Note:

The concentration of the medication after reconstitution is not explicitly provided on the label.

We cannot directly calculate the volume to administer based solely on the prescribed dose (0.0625 mg) and the unknown concentration.

Scenario:

In real-world practice, nurses rely on the medication information sheet or the manufacturer's label for dilution instructions and the final concentration after reconstitution.

This information is crucial for calculating the accurate volume to administer the prescribed dose.

Assuming the medication information sheet specifies:

After reconstitution with 1.2 mL diluent, the final concentration is 0.25 mg/mL. 

 

Calculation (based on the assumed concentration):

Prescribed dose: 0.0625 mg

Volume to administer (mL) = Dose (mg) / Concentration (mg/mL)

Volume to administer (mL) = 0.0625 mg / 0.25 mg/mL

Volume to administer (mL) = 0.25 mL (round to nearest hundredth)

Therefore, based on the assumed concentration after reconstitution (0.25 mg/mL), the nurse should administer 0.25 mL to the client.


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Related Questions

Correct Answer is ["7.5"]

Explanation

Here's how to calculate the concentration (mg/mL) of the reconstituted ceftazidime medication

Medication: 750 mg ceftazidime

Diluent: 100 mL sterile water (for reconstitution)

We need to find the concentration (mg/mL) after reconstituting the medication with diluent.

Calculation:

Concentration (mg/mL) = Total medication (mg) / Volume of diluent (mL)

Concentration (mg/mL) = 750 mg / 100 mL

Concentration (mg/mL) = 7.5 mg/mL (round to nearest tenth)

Therefore, the reconstituted medication will have a concentration of 7.5 mg/mL.

Correct Answer is ["18"]

Explanation

Here's how to calculate the rate (mL/hour) for the infusion pump:

Heparin concentration:

The medication is available in a 250 mL bag containing 20,000 units of heparin.

Heparin concentration (units/mL) = Total heparin (units) / Volume (mL)

Heparin concentration (units/mL) = 20,000 units / 250 mL

Heparin concentration (units/mL) = 80 units/mL (round to nearest whole number)

Prescribed heparin dose: 1,400 units/hour (given)

We need to find the volume delivered per hour (mL/hour) to achieve the prescribed heparin dose (1400 units/hour) considering the concentration (80 units/mL).

Infusion rate (mL/hour) = Dose (units/hour) / Concentration (units/mL)

Infusion rate (mL/hour) = 1400 units/hour / 80 units/mL

Infusion rate (mL/hour) = 17.5 mL/hour (round to nearest whole number)

Therefore, the nurse should program the infusion pump to deliver approximately 18 mL/hour.

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