The healthcare provider prescribes interferon beta-1b 0.0625 mg SUBQ every other day for a client with multiple sclerosis. The nurse reconstitutes the single-use vial of powder labeled, "0.3 mg with 1.2 mL of sterile water." How many mL should the nurse administer to the client? (Enter the numerical value only. If rounding is required, round to the nearest hundredth.)
The Correct Answer is ["0.25"]
Here's how to calculate the volume the nurse should administer after reconstituting the medication:
Reconstitution:
The medication vial is labeled "0.3 mg with 1.2 mL of sterile water." This means adding 1.2 mL of diluent will result in a total volume of 1.2 mL solution.
Important Note:
The concentration of the medication after reconstitution is not explicitly provided on the label.
We cannot directly calculate the volume to administer based solely on the prescribed dose (0.0625 mg) and the unknown concentration.
Scenario:
In real-world practice, nurses rely on the medication information sheet or the manufacturer's label for dilution instructions and the final concentration after reconstitution.
This information is crucial for calculating the accurate volume to administer the prescribed dose.
Assuming the medication information sheet specifies:
After reconstitution with 1.2 mL diluent, the final concentration is 0.25 mg/mL.
Calculation (based on the assumed concentration):
Prescribed dose: 0.0625 mg
Volume to administer (mL) = Dose (mg) / Concentration (mg/mL)
Volume to administer (mL) = 0.0625 mg / 0.25 mg/mL
Volume to administer (mL) = 0.25 mL (round to nearest hundredth)
Therefore, based on the assumed concentration after reconstitution (0.25 mg/mL), the nurse should administer 0.25 mL to the client.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["0.25"]
Explanation
Here's how to calculate the volume the nurse should administer after reconstituting the medication:
Reconstitution:
The medication vial is labeled "0.3 mg with 1.2 mL of sterile water." This means adding 1.2 mL of diluent will result in a total volume of 1.2 mL solution.
Important Note:
The concentration of the medication after reconstitution is not explicitly provided on the label.
We cannot directly calculate the volume to administer based solely on the prescribed dose (0.0625 mg) and the unknown concentration.
Scenario:
In real-world practice, nurses rely on the medication information sheet or the manufacturer's label for dilution instructions and the final concentration after reconstitution.
This information is crucial for calculating the accurate volume to administer the prescribed dose.
Assuming the medication information sheet specifies:
After reconstitution with 1.2 mL diluent, the final concentration is 0.25 mg/mL.
Calculation (based on the assumed concentration):
Prescribed dose: 0.0625 mg
Volume to administer (mL) = Dose (mg) / Concentration (mg/mL)
Volume to administer (mL) = 0.0625 mg / 0.25 mg/mL
Volume to administer (mL) = 0.25 mL (round to nearest hundredth)
Therefore, based on the assumed concentration after reconstitution (0.25 mg/mL), the nurse should administer 0.25 mL to the client.
Correct Answer is ["2.4"]
Explanation
Here's how to calculate the volume (mL) the nurse should administer for cefazolin:
1. We know the following:
Prescribed dose: 800 mg cefazolin IM every 6 hours (given)
Vial content: 1 gram cefazolin (given)
However, we need to consider the reconstitution process for accurate dosage calculation.
Reconstitution information:
For IM use, add 2.5 mL sterile water for injection.
This dilution creates a total volume of 3.0 mL.
3. We need to find the concentration of cefazolin in the reconstituted solution (mg/mL).
Concentration (mg/mL) = Total drug amount (mg) / Total volume (mL) after reconstitution
Concentration (mg/mL) = 1 gram (which is 1000 mg) / 3.0 mL
Concentration (mg/mL) = 333.33 mg/mL (round to nearest tenth)
4. Now, we can find the volume to administer for the prescribed dose (800 mg) considering the concentration (333.33 mg/mL) in the reconstituted solution.
Volume to administer (mL): Dose (mg) / Concentration (mg/mL)
Volume to administer (mL): 800 mg / 333.33 mg/mL
Volume to administer (mL): 2.40 mL (round to nearest tenth)
Therefore, the nurse should administer approximately 2.4 mL of the reconstituted cefazolin solution intramuscularly.
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