The client receives 200 mg of a medication on a consistent schedule. How much drug is in the body at 4 half-lives?
387.5
375
393.8
350
The Correct Answer is B
Here's the process for calculating the drug concentration after multiple half-lives:
First half-life: After 1 half-life, 50% of the original dose remains in the body.
200 mg x 0.50 = 100 mg remains after 1 half-life.
Second half-life: After 2 half-lives, 50% of the remaining drug will be eliminated.
100 mg x 0.50 = 50 mg remains after 2 half-lives.
Third half-life: After 3 half-lives, 50% of the remaining drug will be eliminated again.
50 mg x 0.50 = 25 mg remains after 3 half-lives.
Fourth half-life: After 4 half-lives, 50% of the remaining drug will be eliminated once more.
25 mg x 0.50 = 12.5 mg remains after 4 half-lives.
Now, we need to sum up the amount of drug remaining in the body at each half-life:
After 4 half-lives, there are 12.5 mg left from the original dose.
Total drug in the body after 4 half-lives = 200 mg - 12.5 mg = 375 mg.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A) This medication neutralizes gastric acid in the stomach by direct contact: Sucralfate does not neutralize gastric acid. Instead, it works by forming a protective barrier over the ulcer, which helps protect it from further damage by stomach acid and promotes healing. Sucralfate is a mucosal protectant, not an acid-neutralizing agent.
B) "You should take this medication after meals to help limit gastric acid secretion": Sucralfate should be taken on an empty stomach, typically 30 minutes to 1 hour before meals, to allow it to form an effective protective barrier over the ulcer. Taking it after meals would interfere with its action and effectiveness.
C) "This medication decreases gastric acid production by blocking histamine 2 receptors": Sucralfate does not work by blocking histamine 2 receptors. Histamine 2 receptor antagonists, such as ranitidine, work by reducing gastric acid secretion. Sucralfate works by coating and protecting the ulcer rather than by reducing acid production.
D) "You should take this medication 30 minutes to 1 hour before meals and at bedtime": Sucralfate should be taken on an empty stomach, typically 30 minutes to 1 hour before meals and at bedtime. This timing ensures that the medication can form an effective barrier over the ulcer before food intake and helps maximize its healing properties.
Correct Answer is B
Explanation
A) Right dose: The right dose was administered. The order specifies 1000 mg of
acetaminophen, and the nurse gave 1000 mg. Therefore, the right dose was given, and this is not the issue in this situation.
B) Right route: The right route was not followed in this situation. The order specifies that acetaminophen should be administered IV, but the nurse administered the medication PO. The route of administration is crucial for ensuring the medication is delivered in the appropriate manner for the intended therapeutic effect. By giving the medication orally instead of intravenously, the nurse deviated from the prescribed route, which is a violation of the "right route."
C) Right reason: The right reason was followed because acetaminophen is commonly given for pain or fever management, and no information suggests the wrong reason for administering the drug. The nurse's action doesn’t indicate a mistake in the reasoning for giving the medication.
D) Right time: The right time is not affected here, as the nurse did administer the acetaminophen at the scheduled time. The issue is with the route, not the timing.
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