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Pepsinogen is produced by______________ and is activated by__________

A.

chief cells; hydrochloric acid (HCI): parietal cells

B.

chief cells; carbonic anhydrase (CAH); parietal cells

C.

parietal cells; carbonic anhydrase (CAH); chief cells

D.

parietal cells; hydrochloric acid (HCI); chief cells

Answer and Explanation

The Correct Answer is A

A. Chief cells; hydrochloric acid (HCl); parietal cells: Pepsinogen is produced by chief cells, and it is activated into pepsin by hydrochloric acid (HCl) secreted by parietal cells.

B. Chief cells; carbonic anhydrase (CAH); parietal cells: Chief cells produce pepsinogen, but it is not activated by carbonic anhydrase. Instead, it is activated by HCl.

C. Parietal cells; carbonic anhydrase (CAH); chief cells: Pepsinogen is produced by chief cells, not parietal cells, and its activation involves HCl, not carbonic anhydrase.

D. Parietal cells; hydrochloric acid (HCl); chief cells: Pepsinogen is produced by chief cells, not parietal cells, and is activated by HCl.


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