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Order: dobutamine 5 mcg/kg/min

Patient's weight: 152 lb

Available: dobutamine 500 mg in 250 mL D5W

What is the flow rate in ml/hr? (Round to the nearest tenths)

A.

9 mL/hr

B.

103.5 mL/hr

C.

11 mu/hr

D.

10.4 mL/hr

Answer and Explanation

The Correct Answer is D

1. Convert patient weight from pounds to kilograms:

Patient weight (kg) = 152 lb x 0.453592 kg/lb = 68.94 kg

2. Calculate the desired dose in mcg/min:

Desired dose (mcg/min) = 5 mcg/kg/min x 68.94 kg = 344.7 mcg/min

3. Convert mcg/min to mg/min:

Desired dose (mg/min) = 344.7 mcg/min / 1000 mcg/mg = 0.3447 mg/min

4. Calculate the concentration of dobutamine in the solution:

Concentration (mg/mL) = 500 mg / 250 mL = 2 mg/mL

5. Calculate the flow rate in mL/min:

Flow rate (mL/min) = Desired dose (mg/min) / Concentration (mg/mL)

Flow rate (mL/min) = 0.3447 mg/min / 2 mg/mL = 0.17235 mL/min

6. Calculate the flow rate in mL/hr:

Flow rate (mL/hr) = 0.17235 mL/min x 60 min/hr = 10.341 mL/hr

7. Round to the nearest tenth:

Flow rate (mL/hr) = 10.3 mL/hr

Therefore, the correct answer is 10.4 mL/hr


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Related Questions

Correct Answer is B

Explanation

Given:

Ordered dose of hydrocortisone: 100 mg

Concentration of hydrocortisone: 250 mg/2 mL

Step 1: Set up the proportion:

Desired dose (mg) / Volume to administer (mL) = Concentration (mg/mL)

Step 2: Substitute the values:

100 mg / Volume = 250 mg/2 mL

Step 3: Solve for the unknown volume:

Volume = 100 mg / (250 mg/2 mL)

Volume = 100 mg x (2 mL / 250 mg)

Volume = 0.8 mL

Correct Answer is C

Explanation

A) Bradycardia
Bradycardia (a slow heart rate) is not the most common response to nitroglycerin (NTG). While NTG can affect heart rate in some individuals, its primary action is related to blood vessels, and it typically leads to vasodilation, which more commonly results in reflex tachycardia (an increased heart rate), rather than bradycardia.

B) Tachycardia
Tachycardia (an increased heart rate) can occur as a compensatory mechanism when nitroglycerin causes vasodilation and a decrease in blood pressure. However, this is more of a secondary effect. The primary action of nitroglycerin is to lower blood pressure (by dilating blood vessels), and in response to the lowered blood pressure, the body may try to compensate by increasing the heart rate.

C) Hypotension
The most common and primary response to nitroglycerin (NTG) administration is hypotension. Nitroglycerin works by relaxing smooth muscle in blood vessels, leading to vasodilation (widening of blood vessels). This reduces the amount of work the heart has to do and lowers the overall blood pressure. Hypotension is expected as part of the therapeutic effect of NTG, especially with a larger dose or rapid administration (e.g., sublingual NTG).

D) Dry mouth
While many medications can cause dry mouth (especially anticholinergic drugs), nitroglycerin is not typically associated with this issue. Its primary action is vasodilation, and while it can cause other symptoms like headaches, dizziness, and hypotension, dry mouth is not considered a common or significant effect.

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