How does genetic predisposition contribute to the development of psoriasis?
Genetic factors increase skin sensitivity to environmental irritants
Genetic factors cause an allergic reaction to certain foods
Genetic factors lead to abnormal immune system functioning
Genetic factors impair the skin's barrier function
The Correct Answer is C
Explanation: Genetic predisposition in psoriasis contributes to the development of the condition by causing abnormal functioning of the immune system. Certain genes involved in the immune response are associated with psoriasis, leading to an overactive immune system that triggers inflammation and skin cell overproduction.
Incorrect choices: a. Genetic factors increase skin sensitivity to environmental irritants: While some environmental triggers can worsen psoriasis symptoms, genetic predisposition primarily influences the immune system's response, not skin sensitivity to irritants.
b. Genetic factors cause an allergic reaction to certain foods: Psoriasis is not primarily an allergic reaction, and genetic factors do not cause allergic reactions to specific foods in this context.
d. Genetic factors impair the skin's barrier function: Psoriasis is not caused by a skin barrier dysfunction. The condition is characterized by immune system dysregulation and the subsequent inflammation and rapid skin cell turnover.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Explanation: Psoriasis commonly affects the scalp and nails in addition to other areas of the body. Scalp psoriasis can cause flaking and scale buildup on the scalp, while nail psoriasis can lead to pitting, discoloration, and thickening of the nails.
Incorrect choices: b. Buttocks and thighs: While psoriasis can occur in these areas, it is not one of the most common areas affected.
c. Lower back and shoulders: These areas can be affected by psoriasis, but they are not the most commonly affected regions.
d. Upper arms and neck: Psoriasis can occur on the upper arms and neck, but it is not the most frequently affected area.
Correct Answer is C
Explanation
Explanation: The presence of at least 3 typical psoriasis plaques on the body is one of the essential diagnostic criteria for confirming psoriasis. These plaques are characterized by well-defined, erythematous (red), raised lesions with silvery-white scales.
Incorrect choices: a. Positive skin biopsy showing eosinophils infiltration: While a skin biopsy may be performed to support the diagnosis of psoriasis, the presence of eosinophils is not specific to psoriasis and can be found in various skin conditions.
b. Family history of autoimmune diseases: A family history of autoimmune diseases may increase the risk of developing psoriasis, but it is not a definitive diagnostic criterion for the condition.
d. Elevated erythrocyte sedimentation rate (ESR) on blood test: An elevated ESR can indicate inflammation in the body, but it is not specific to psoriasis and may be present in other inflammatory conditions as well.
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