Exhibits

The provider would like the client to continue with the captopril dose and restart the spironolactone. The provider wants the client to return to the clinic in 6 weeks with lab work done.

What 2 labs would be most appropriate for this client to complete on their return visit?

Choice A rationale: Non-steroidal anti-inflammatory drugs (NSAIDs) are a different class of
medications commonly used to relieve pain, inflammation, and reduce fever. They are not used
for treating hypertension or acting as ACE inhibitors.
Choice B rationale: Angiotensin II receptor blockers (ARBs) are another class of
antihypertensive medications that work by blocking the action of angiotensin II, a hormone that
causes blood vessels to constrict. While ARBs are similar in function to ACE inhibitors in
managing blood pressure, captopril specifically belongs to the ACE inhibitor class.
Choice C rationale: Captopril is an angiotensin-converting enzyme (ACE) inhibitor. ACE
inhibitors are a class of antihypertensive medications that work by inhibiting the enzyme ACE,
which converts angiotensin I to angiotensin II. By inhibiting this conversion, ACE inhibitors
help relax and dilate blood vessels, leading to decreased blood pressure. They are commonly
used to treat hypertension and other cardiovascular conditions.
Choice D rationale: Aldosterone antagonists are a different class of medications used to block the
action of aldosterone, a hormone that regulates sodium and water balance in the body. They are
used to manage conditions such as heart failure and hypertension but are not synonymous with ACE inhibitors like captopril.

Choice A rationale: Quinapril is an ACE inhibitor and, like captopril, is typically given twice daily. It does not have an extended duration of action that would allow for once-daily dosing.

Choice B rationale: Lisinopril is an ACE inhibitor that can be given once per day. It has a long duration of action, which allows for once-daily dosing. This makes it a convenient option for patients who have difficulty remembering to take their medications multiple times a day.

Choice C rationale: Ramipril is another ACE inhibitor that can be given once per day. Like lisinopril, it has an extended duration of action, allowing for once-daily dosing.

Choice D rationale: Trandolapril is an ACE inhibitor that can also be given once per day. It has a prolonged duration of action, which supports once-daily dosing for optimal blood pressure control.

Choice E rationale: Captopril itself is listed in the options, and it is not an ACE inhibitor that can be given only once per day. Captopril has a short duration of action and is usually prescribed for twice-daily dosing.