A nurse is reviewing the results of an Alpha-fetoprotein Test (AFP) with a pregnant client.
What does a low level of AFP (<0.5 MoM) potentially indicate?
Neural tube defect.
Chromosomal abnormality.
Maternal weight-related factors.
Fetal demise.
The Correct Answer is B
A low level of AFP (<0.5 MoM) in a pregnant woman can indicate that the fetus has a chromosomal abnormality, such as Down syndrome or Edwards syndrome.
This is because these conditions affect the development of the fetal liver, which produces AFP.
Choice A is wrong because neural tube defects, such as spina bifida, are associated with high levels of AFP (>2.5 MoM) in the maternal blood.
This is because AFP can leak from the open spinal canal of the fetus into the amniotic fluid and then into the maternal blood.
Choice C is wrong because maternal weight-related factors do not affect the level of AFP in the maternal blood.
However, they can affect the interpretation of the AFP test results, as the test needs to be adjusted for maternal weight, age, ethnicity, and gestational age.
Choice D is wrong because fetal demise (death) can also cause high levels of AFP in the maternal blood, as the AFP from the dead fetus can leak into the amniotic fluid and then into the maternal blood.
Normal ranges of AFP in pregnant women vary depending on the gestational age and the method of measurement.
Generally, normal levels of AFP are below 10 ng/ml in nonpregnant adults and below 2.5 MoM in pregnant women.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
The correct answer is choice D. The client has a history of placenta previa.
Placenta previa is a condition where the placenta covers all or part of the cervix, blocking the baby’s exit from the uterus.
This can cause severe bleeding during pregnancy and delivery and increase the risk of complications for both the mother and the baby.
Therefore, the nurse should report this condition to the provider before performing an amniocentesis.
Choice A is wrong because having Rh-negative blood type is not a contraindication for amniocentesis.
However, the client may need an injection of Rh immunoglobulin after the procedure to prevent Rh sensitization.
Choice B is wrong because having a history of preterm labor is not a contraindication for amniocentesis.
However, the client may need to be monitored closely for signs of preterm labor after the procedure.
Choice C is wrong because having a history of gestational diabetes is not a contraindication for amniocentesis.
However, the client may need to have their blood glucose levels checked before and after the procedure.
Amniocentesis is a diagnostic procedure that involves removing and testing a small sample of amniotic fluid from the uterus for genetic or chromosomal conditions, such as Down syndrome, Edwards syndrome or Patau syndrome.
It can also be used to diagnose fetal infections, treat excess amniotic fluid, or test fetal lung maturity
Correct Answer is A
Explanation
Normal level of AFP for the given gestational age.
AFP is a protein that the liver makes when its cells are growing and dividing to make new cells.
It is normally high in unborn babies and drops very low after birth.
The AFP test measures the amount of AFP present in blood and can help diagnose certain types of cancer and check how well treatment is working.
It can also help detect some birth defects in pregnant women.
Choice B is wrong because high level of AFP indicating a neural tube defect.
Neural tube defects are abnormalities that affect the brain and spinal cord of the fetus.
They can cause spina bifida, which is a condition where the spine does not close properly.
High levels of AFP can be a sign of neural tube defects, but they can also be caused by other factors, such as multiple pregnancies, inaccurate dating of pregnancy, or fetal death.
Choice C is wrong because low level of AFP indicating a chromosomal abnormality.
Chromosomal abnormalities are genetic disorders that affect the number or structure of chromosomes in the fetus.
They can cause Down syndrome, which is a condition where the fetus has an extra copy of chromosome 212.
Low levels of AFP can be a sign of chromosomal abnormalities, but they can also be caused by other factors, such as inaccurate dating of pregnancy, fetal death, or maternal obesity.
Choice D is wrong because inconclusive result, requiring further evaluation.
An inconclusive result means that the AFP level is neither too high nor too low to indicate a problem with the fetus.
It does not necessarily mean that there is something wrong with the fetus, but it may require further testing to confirm or rule out any abnormalities.
Normal ranges for AFP levels vary depending on the gestational age and the laboratory that performs the test.
Generally, the normal range for AFP levels in pregnant
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