A nurse is preparing to administer ephedrine 3 mg/kg/day IV bolus divided in equal doses every 6 hr to a school-age child who weighs 70 lb. Available is ephedrine injection 50 mg/mL. How many mL should the nurse administer per dose?
(Round the answer to the nearest hundredth. Use a leading zero if it applies. Do not use a trailing zero.)
The Correct Answer is ["0.48"]
To calculate this, first convert the child's weight from pounds to kilograms: 70 lb * (1 kg / 2.2 lb) = 31.82 kg. Then, calculate the total daily dose of ephedrine in mg: 3 mg/kg/day * 31.82 kg/day = 95.45 mg/day.
Since the daily dose is divided into equal doses every 6 hours, calculate the dose per administration: 95.45 mg/day / (24 hr/day / 6 hr/dose) = 23.86 mg/dose.
Finally, divide the dose in mg by the concentration of the ephedrine injection to find the volume to administer: 23.86 mg / (50 mg/mL) = 0.477 mL, which rounds to 0.48 mL when rounded to the nearest hundredth.
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Related Questions
Correct Answer is ["11.6"]
Explanation
To calculate this, first convert the child's weight from pounds to kilograms: 64 lb * (1 kg / 2.2 lb) = 29.09 kg. Then, calculate the dose of vancomycin in mg: 20 mg/kg * 29.09 kg = 581.8 mg.
Finally, divide the dose in mg by the concentration of the vancomycin injection to find the volume to administer: 581.8 mg / (50 mg/mL) = 11.636 mL/dose, which rounds to 11.6 mL when rounded to the nearest tenth.
Correct Answer is ["4.2"]
Explanation
Step 1: Convert the preschooler’s weight from pounds to kilograms. 37 lbs ÷ 2.2 = 16.8181 kg (rounded to four decimal places)
Step 2: Calculate the total daily dose of cephalexin in mg. 50 mg/kg/day × 16.8181 kg = 840.905 mg/day (rounded to three decimal places)
Step 3: Determine the number of doses per day. 24 hours ÷ 6 hours = 4 doses/day
Step 4: Calculate the dose per administration. 840.905 mg/day ÷ 4 doses/day = 210.22625 mg/dose (rounded to five decimal places)
Step 5: Convert the dose from mg to mL using the available suspension concentration. 250 mg ÷ 5 mL = 50 mg/mL
Step 6: Calculate the volume to be administered per dose. 210.22625 mg ÷ 50 mg/mL = 4.204525 mL (rounded to six decimal places)
Step 7: Round the final answer to the nearest tenth. 4.204525 mL rounded to the nearest tenth = 4.2 mL
Therefore, the nurse should administer 4.2 mL per dose.
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