A nurse is preparing to administer antiviral therapy.
The nurse integrates knowledge of this therapy, administering the drugs cautiously to clients with which of the following?
Hepatic impairment.
Renal impairment.
Diabetes.
Hypertension.
The Correct Answer is A
Choice A rationale:
Antiviral drugs are metabolized in the liver, and hepatic impairment can affect the metabolism and elimination of these drugs. Therefore, the nurse should administer antiviral therapy cautiously to clients with hepatic impairment to prevent potential drug toxicity. Hepatic impairment can alter the pharmacokinetics of antiviral drugs, leading to increased drug levels in the bloodstream.
Choice B rationale:
Renal impairment is not typically a contraindication for antiviral therapy. While some medications may require dose adjustments in patients with renal impairment, it is not a general concern for antiviral drugs. The primary organ responsible for the metabolism of antiviral drugs is the liver.
Choice C rationale:
Diabetes and hypertension are chronic medical conditions that are not directly related to the administration of antiviral therapy. These conditions do not significantly impact the pharmacokinetics or pharmacodynamics of antiviral drugs. Therefore, they are not primary factors to consider when administering antiviral therapy.
Choice D rationale:
Hypertension, like diabetes, is not directly related to the administration of antiviral therapy. Antiviral drugs primarily interact with the liver's metabolic pathways, and hypertension does not have a significant impact on drug metabolism.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale:
Emetics are medications that induce vomiting and are used in cases of drug overdose, ingestion of toxic substances, or other situations where rapid removal of the ingested substance is necessary. However, it is crucial that the client's mental status is intact and they can cooperate and understand the need to induce vomiting. If a client is unconscious or unable to protect their airway, inducing vomiting can lead to aspiration and further complications.
Choice B rationale:
Clients with existing severe hypertension should not be administered emetics, as the act of inducing vomiting can lead to a sudden increase in blood pressure, potentially causing adverse cardiovascular events.
Choice C rationale:
Clients with a medical history of convulsions (seizures) should not be given emetics. Inducing vomiting may lead to a convulsive episode, which can be harmful and increase the risk of aspiration.
Choice D rationale:
Clients with an existing condition of hemorrhagic diathesis (a tendency to bleed excessively) should not be administered emetics. Inducing vomiting can cause mucosal damage and bleeding in the gastrointestinal tract, further exacerbating the client's condition.
Correct Answer is A
Explanation
Choice A rationale:
Alkylating agents are cell cycle-specific drugs. They work on cells during various stages of the cell cycle and are classified as cell cycle phase-nonspecific drugs. These drugs form covalent bonds with DNA, preventing DNA replication and transcription. This action disrupts the cell cycle, making them effective against actively dividing cells.
Choice B rationale:
Plant alkaloids are not cell cycle-specific drugs. Plant alkaloids, such as vinblastine and vincristine, are derived from plants and are classified as cell cycle phase-specific drugs. They primarily affect cells during the M phase of the cell cycle by disrupting microtubule formation. While they are effective against rapidly dividing cells, they are not cell cycle-specific.
Choice C rationale:
Antineoplastic antibiotics are not cell cycle-specific drugs. These drugs, such as doxorubicin and daunorubicin, are used in cancer treatment and primarily work by intercalating with DNA and inhibiting topoisomerase enzymes. Their mechanisms of action do not specifically target a particular phase of the cell cycle, making them cell cycle phase-nonspecific.
Choice D rationale:
Retinoids are not cell cycle-specific drugs. Retinoids are derived from vitamin A and have various mechanisms of action, including regulating cell growth and differentiation. They are not classified as cell cycle-specific drugs.
Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.
Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today
Report Wrong Answer on the Current Question
Do you disagree with the answer? If yes, what is your expected answer? Explain.
Kindly be descriptive with the issue you are facing.