A nurse is preparing to administer albuterol syrup 1.6 mg PO tid. Available is albuterol 2 mg/5mL. How many mL should the nurse administer per dose? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

A. Increased arterial oxygen: Clients with COPD typically experience chronic hypoxemia due to alveolar destruction, airway inflammation, and mucus production, which impair gas exchange. Rather than increased oxygen levels, they often have a decreased PaO₂, requiring supplemental oxygen therapy. However, excessive oxygen administration can suppress their respiratory drive, worsening CO₂ retention.
B. Increased pH: COPD is associated with respiratory acidosis due to chronic CO₂ retention from inadequate alveolar ventilation. While the kidneys compensate by increasing bicarbonate retention, the pH usually remains low or near normal in chronic cases rather than becoming elevated. A higher pH would indicate alkalosis, which is not typical in COPD unless there is an additional metabolic disturbance.
C. Increased carbon dioxide: COPD causes airway obstruction and reduced alveolar ventilation, leading to CO₂ retention (hypercapnia). As CO₂ accumulates in the blood, it lowers the pH, resulting in respiratory acidosis. Chronic hypercapnia is a hallmark of advanced COPD, and in response, the kidneys retain bicarbonate to partially compensate, stabilizing the pH over time but leaving PaCO₂ elevated.
D. Decreased alveolar function: While COPD does lead to progressive alveolar damage and reduced gas exchange, this is a structural and functional change rather than a specific abnormality seen in arterial blood gases. The primary ABG finding in COPD is hypercapnia, which reflects inadequate ventilation and CO₂ retention rather than just decreased alveolar function alone.

A. To facilitate weaning off the mechanical ventilator. While PEEP is an important component of mechanical ventilation, its primary function is not to facilitate weaning. Instead, it improves oxygenation by preventing alveolar collapse. Weaning involves gradually reducing ventilatory support, but PEEP is typically adjusted based on oxygenation needs rather than as a direct step in weaning.
B. To decrease trapped oxygen in the alveoli. PEEP does not decrease trapped oxygen; instead, it maintains alveolar patency and prevents atelectasis. In conditions like ARDS, alveoli tend to collapse due to fluid accumulation and inflammation, and PEEP helps counteract this collapse to improve gas exchange. Reducing "trapped" oxygen is not a function of PEEP.
C. To promote independent breathing efforts. PEEP itself does not promote spontaneous breathing; instead, it provides positive pressure at the end of exhalation to improve oxygenation. In fact, high levels of PEEP can suppress spontaneous breathing by increasing intrathoracic pressure, requiring careful adjustment to balance oxygenation and ventilatory effort.
D. To keep the airways and small lung spaces open. PEEP prevents alveolar collapse by maintaining positive pressure in the lungs at the end of expiration. This improves oxygenation and gas exchange, which is critical in ARDS, where alveoli are prone to collapse due to inflammation and fluid accumulation. Keeping alveoli open reduces shunting and improves oxygen delivery to tissues.