A nurse is preparing an in-service about all the phases of pharmacokinetics.
Which of the following is NOT a phase of pharmacokinetics?
Excretion.
Phlebitis.
Distribution.
Absorption.
The Correct Answer is B
Choice A rationale
Excretion is a phase of pharmacokinetics where the drug or its metabolites are eliminated from the body, primarily via the kidneys.
Choice B rationale
Phlebitis is inflammation of a vein and is not a phase of pharmacokinetics. It is a medical condition rather than a pharmacokinetic process.
Choice C rationale
Distribution is a phase of pharmacokinetics where the drug is dispersed throughout the body’s tissues and fluids after absorption.
Choice D rationale
Absorption is a phase of pharmacokinetics where the drug is absorbed into the bloodstream from the site of administration.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale
Simvastatin is used to lower cholesterol levels and is not indicated for the management of DVT.
Choice B rationale
Furosemide is a diuretic used to treat fluid retention and high blood pressure, not DVT.
Choice C rationale
Enoxaparin is an anticoagulant that helps to prevent and treat deep vein thrombosis by inhibiting clot formation.
Choice D rationale
Gemfibrozil is used to reduce triglyceride levels and is not indicated for DVT management.
Correct Answer is B
Explanation
Choice A rationale
Celecoxib does not inhibit the histamine response. Histamine is involved in allergic reactions, and celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that targets specific enzymes involved in inflammation.
Choice B rationale
Celecoxib specifically inhibits COX-2, an enzyme involved in the inflammation pathway. This selective inhibition helps reduce inflammation and pain without significantly affecting COX-1, which is protective for the stomach lining.
Choice C rationale
COX-1 is not the primary target of celecoxib. Inhibition of COX-1 can lead to gastrointestinal side effects, which celecoxib aims to minimize by selectively inhibiting COX-2 instead.
Choice D rationale
Celecoxib does not inhibit beta receptors. Beta receptors are involved in cardiovascular responses, and beta blockers are used for conditions like hypertension, not inflammation.
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