A nurse is instructing a colleague on how an antimicrobial produces a therapeutic effect. What should be included in the nurse's teaching?
The first drugs used to treat infections date back to the 17th century.
Fluoroquinolones interfere with the growth and development of the bacteria cell wall.
Selective toxicity determines the appropriate drug dosage needed.
Penicillin interferes with synthesis of the bacteria cell wall.
The Correct Answer is D
A. While historical context is useful, the development of antimicrobials primarily began in the early 20th century, notably with penicillin discovered by Alexander Fleming in 1928.
B. This statement is incorrect; fluoroquinolones primarily inhibit bacterial DNA synthesis rather than directly affecting the cell wall.
C. Selective toxicity is a principle of antimicrobial action but does not directly explain how a specific antimicrobial works therapeutically.
D. Penicillin specifically interferes with the synthesis of the bacterial cell wall, leading to cell lysis and death of the bacteria, which is a fundamental mechanism of action for this antibiotic.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Take the drug on an empty stomach is correct because tetracycline should be taken without food for optimal absorption, ideally 1 hour before or 2 hours after meals.
B. Take the drug along with a meal is incorrect as it can reduce the absorption of tetracycline.
C. Take the drug along with milk or fruit juice is incorrect because calcium and magnesium can bind to tetracycline, decreasing its effectiveness.
D. Take the drug immediately after meals is also incorrect as food can hinder absorption, making this timing ineffective for treatment.
Correct Answer is B
Explanation
A. While assessing potassium levels is important for clients on diuretics, the immediate concern is the client's dizziness, which indicates a potential issue with blood pressure.
B. Teaching the client about the potential for orthostatic hypotension caused by hydrochlorothiazide and instructing them on safety measures (e.g., standing up slowly) is crucial to prevent falls and address the dizziness.
C. Bed rest is not necessary; the client should be educated about managing dizziness instead.
D. Withholding the medication is not warranted unless directed by a healthcare provider; the focus should be on safety education.
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