A nurse is discussing the factors that can affect Alpha-fetoprotein Test (AFP) results with a pregnant client.
Which factor should the nurse mention?
Maternal weight.
Fetal heart rate.
Gestational age.
Placental function.
The Correct Answer is C
The level of AFP in a pregnant woman’s blood depends on how far along she is in her pregnancy.
AFP levels are normally high in the early weeks of pregnancy and then decline as the pregnancy progresses.
If the AFP level is too high or too low for the gestational age, it may indicate a problem with the baby’s development.
Choice A is wrong because maternal weight does not affect AFP levels.
Choice B is wrong because fetal heart rate does not affect AFP levels.
Choice D is wrong because the placental function does not affect AFP levels directly, but it may affect the levels of other hormones that are measured along with AFP in a quad screen.
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Correct Answer is A
Explanation
The test involves an ultrasound and a nonstress test.
A biophysical profile (BPP) is a way to check on the overall fetal health by observing the fetus’s heart rate, breathing, movement, muscle tone, and the amount of amniotic fluid surrounding the fetus in the uterus.
It is typically performed after 28 weeks of pregnancy, especially for high-risk pregnancies or if there is a chance of complications.
Choice B is wrong because a contraction stress test is not part of a BPP.
A contraction stress test measures how the fetus’s heart rate changes during contractions induced by oxytocin or nipple stimulation.
It is a different test from a nonstress test, which measures the fetus’s heart rate while moving and at rest without any stimulation.
Choice C is wrong because a Doppler ultrasound is not part of a BPP.
A Doppler ultrasound uses sound waves to measure the blood flow in the umbilical cord and other blood vessels.
It is a different type of ultrasound from the one used in a BPP, which uses sound waves to create images of the fetus and the amniotic fluid.
Choice D is wrong because it combines two incorrect components from choices B and C. A BPP does not involve a Doppler ultrasound or a contraction stress test.
Correct Answer is A
Explanation
This is because AFP levels vary according to the gestational age of the fetus, and reporting them as multiples of the median (MoM) allows for a standardized comparison.
Choice B is wrong because AFP results do not differentiate between neural tube defects and chromosomal abnormalities.
They only indicate an increased risk for these conditions, which need further testing to confirm.
Choice C is wrong because AFP results do not assess the risk of fetal demise or multiple gestation.
They only measure the amount of AFP in the maternal blood, which can be affected by various factors such as maternal weight, race, diabetes, and fetal anomalies.
Choice D is wrong because AFP results are reported as MoM regardless of factors such as maternal weight and race.
These factors are taken into account when calculating the MoM value, which adjusts for the expected variation in AFP levels among different populations.
Normal ranges for AFP MoM vary depending on the laboratory and the method used, but generally they are between 0.5 and 2.52.
Values above or below this range may indicate an increased risk for certain fetal conditions or complications.
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