A nurse is discussing the factors that can affect Alpha-fetoprotein Test (AFP) results with a pregnant client.
Which factor should the nurse mention?
Maternal weight.
Fetal heart rate.
Gestational age.
Placental function.
The Correct Answer is C
The level of AFP in a pregnant woman’s blood depends on how far along she is in her pregnancy.
AFP levels are normally high in the early weeks of pregnancy and then decline as the pregnancy progresses.
If the AFP level is too high or too low for the gestational age, it may indicate a problem with the baby’s development.
Choice A is wrong because maternal weight does not affect AFP levels.
Choice B is wrong because fetal heart rate does not affect AFP levels.
Choice D is wrong because the placental function does not affect AFP levels directly, but it may affect the levels of other hormones that are measured along with AFP in a quad screen.
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Correct Answer is B
Explanation
This test can detect genetic disorders.
Chorionic villus sampling (CVS) is a prenatal test that involves taking a sample of tissue from the placenta to test for chromosomal abnormalities and certain other genetic problems.
The placenta is a structure in the uterus that provides blood and nutrients from the mother to the fetus.
Choice A is wrong because CVS does not provide information on neural tube defects, such as spina bifida.
For this reason, women who undergo CVS also need a follow-up blood test between 16 to 18 weeks of their pregnancy to screen for neural tube defects.
Choice C is wrong because CVS can detect chromosomal abnormalities, but not all chromosomal abnormalities are genetic disorders.
For example, Down syndrome is a chromosomal abnormality caused by an extra copy of chromosome 21, but it is not inherited from the parents.
Choice D is wrong because CVS cannot detect Rh sensitization, which is a condition where the mother’s immune system produces antibodies against the fetus’s blood type.
Rh sensitization can be detected by a blood test that measures the level of antibodies in the mother’s blood.
Correct Answer is A
Explanation
An alpha-fetoprotein test (AFP) is a blood test that measures the amount of AFP present in blood.
It’s usually part of what’s called a triple screen or quad screen in the second trimester of pregnancy.
The yolk sac, GI tract, and liver of an unborn baby produce AFP.
It then circulates through the fetal and maternal blood.
High levels of AFP in pregnant people can indicate that the baby has a neural tube defect, such as spina bifida or anencephaly.
Choice B is wrong because assessing placental function is not the primary purpose of an AFP test.
However, low levels of AFP can indicate problems with the placenta or the baby’s growth.
Choice C is wrong because determining fetal gender is not the primary purpose of an AFP test.
However, some genetic tests that use a sample of the baby’s DNA from the pregnant person’s blood can reveal the baby’s sex as early as 10 weeks of pregnancy.
Choice D is wrong because diagnosing chromosomal abnormalities is not the primary purpose of an AFP test.
However, an AFP test is usually part of a quad screen that also tests for other markers that can indicate the risk of chromosomal abnormalities, such as Down syndrome.
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