A nurse in a provider's clinic is caring for a client who reports erectile dysfunction and requests a prescription for sildenafil. Which of the following medications currently prescribed for the client is a contraindication to taking sildenafil?

Rationale:

A. Metronidazole: Metronidazole is an antibiotic and does not have significant interactions with sildenafil.

B. Phenytoin: Phenytoin is an anticonvulsant medication and does not have significant interactions with sildenafil.

C. Prednisone: Prednisone is a corticosteroid and does not have significant interactions with sildenafil.

D. Isosorbide: Isosorbide is a nitrate medication used to treat angin

A. Combining sildenafil with nitrate medications can lead to severe hypotension and is contraindicated. Sildenafil potentiates the vasodilatory effects of nitrates, which can result in a dangerous drop in blood pressure.

Rationale:

A. Green penile discharge is not a typical finding in genital herpes. Discharge associated with genital herpes is usually clear or cloudy and may be accompanied by pain or itching.

B. Influenza-like symptoms, such as fever, headache, muscle aches, and fatigue, are common manifestations of genital herpes. However, they are not specific to the condition and can occur with various viral infections.

C. Anuria, or the absence of urine production, is not associated with genital herpes. It is a symptom of renal dysfunction or urinary tract obstruction.

D. White- or flesh-colored papillary growths in the genital area, known as genital warts or condylomata acuminata, are a characteristic finding of genital herpes caused by HSV 2. These growths are typically painless but can cause itching or discomfort.