A client with seasonal allergies takes diphenhydramine at bedtime to help their symptoms. The client develops low hemoglobin low white blood cell counts which is otherwise unexplained. What type of reaction is the client experiencing?
Hypersensitivity reaction
Paradoxical reaction
Idiosyncratic reaction
Anti-cholinergic reaction
The Correct Answer is C
A) Hypersensitivity reaction: A hypersensitivity reaction typically involves an immune response where the body reacts to a substance as if it were harmful, leading to symptoms like rashes, swelling, or difficulty breathing. However, low hemoglobin and low white blood cell counts are not typical signs of a hypersensitivity reaction. This would involve more common allergic symptoms like itching or swelling, rather than hematologic changes.
B) Paradoxical reaction: A paradoxical reaction refers to when a medication causes an effect opposite to the expected result. For example, a sedative causing agitation instead of sleepiness. While a paradoxical reaction can involve unexpected effects, the hematologic changes (low hemoglobin and white blood cell counts) in this scenario do not align with this type of response.
C) Idiosyncratic reaction: An idiosyncratic reaction is an unusual or unexpected response to
a medication that is not related to the drug's pharmacologic properties or the dose given. It may be related to genetic factors or other individual differences in how a person metabolizes or responds to the drug. The low hemoglobin and low white blood cell counts in this case are unusual effects of diphenhydramine and suggest an idiosyncratic response, where the client’s body is reacting in an unexpected way to the medication.
D) Anti-cholinergic reaction: Anti-cholinergic reactions are typically related to symptoms caused by the blocking of acetylcholine, such as dry mouth, blurred vision, urinary retention, or constipation. While diphenhydramine has anti-cholinergic properties, the symptoms described (low hemoglobin and white blood cell counts) are not typical of an anti-cholinergic reaction.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A) "I will wash the inhaler once a week with running warm water.": This statement is accurate. It is important to wash the inhaler, especially the mouthpiece, at least once a week to prevent the build-up of medication residue and ensure proper function. The recommendation of using warm water is appropriate, and washing weekly is commonly advised by healthcare providers.
B) "I will administer the second puff 1 minute following the first puff.": This is correct. When using a metered-dose inhaler, it is recommended to wait about 1 minute between puffs to allow the medication to be inhaled properly and for the first dose to be fully delivered before administering the second dose. This ensures that each dose is effective.
C) "I will rinse my mouth with water or mouthwash after inhaler use.": This is a correct statement, particularly for inhaled corticosteroids. Rinsing the mouth after using an inhaler helps prevent the development of oral thrush and other side effects such as irritation or infection. It’s also a good habit to remove any leftover medication from the mouth.
D) "I will take slow deep breaths while activating the inhaler.": This statement indicates the need for additional education. The correct technique involves inhaling slowly and deeply after activating the inhaler, not while activating it. If the client exhales forcefully while pressing the inhaler, they may not be able to inhale the medication effectively. It is crucial that the client activates the inhaler and then takes a slow, deep breath to ensure the medication is delivered properly into the lungs.
Correct Answer is C
Explanation
Here’s the step-by-step process:
After the first half-life (1 half-life), 50% of the initial drug is left.
200 mg → 100 mg (half is eliminated, 100 mg remains).
After the second half-life (2 half-lives), 50% of the remaining drug is eliminated again.
100 mg → 50 mg (half of 100 mg is eliminated, 50 mg remains).
After the third half-life (3 half-lives), 50% of the remaining drug is eliminated again.
50 mg → 25 mg (half of 50 mg is eliminated, 25 mg remains).
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