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Immunity and Hypersensitivity
Immunity and Hypersensitivity ( 5 Questions)
Type II hypersensitivity is caused by the binding of IgG or IgM antibodies to antigens on the surface of target cells. This leads to complement activation, opsonization, phagocytosis, or antibody-dependent cellular cytotoxicity (ADCC) of the target cells. It is seen in conditions such as hemolytic anemia, transfusion reactions, or Graves' disease.
Type III hypersensitivity is caused by the deposition of immune complexes in the tissues and blood vessels. This leads to complement activation, inflammation, and tissue damage. It is seen in conditions such as systemic lupus erythematosus (SLE), rheumatoid arthritis, or serum sickness.
Type IV hypersensitivity is caused by the activation of cytotoxic T cells or helper T cells that release cytokines and recruit macrophages and other inflammatory cells. This leads to delayed and cell-mediated reactions, such as contact dermatitis, tuberculin reaction, or graft rejection.
Choice A reason: Type II hypersensitivity is caused by the binding of IgG or IgM antibodies to antigens on the surface of target cells. This leads to complement activation, opsonization, phagocytosis, or antibody-dependent cellular cytotoxicity (ADCC) of the target cells. It is seen in conditions such as hemolytic anemia, transfusion reactions, or Graves' disease.
Choice B reason: Type III hypersensitivity is caused by the deposition of immune complexes in the tissues and blood vessels. This leads to complement activation, inflammation, and tissue damage. It is seen in conditions such as systemic lupus erythematosus (SLE), rheumatoid arthritis, or serum sickness.
Choice C reason: Type IV hypersensitivity is caused by the activation of cytotoxic T cells or helper T cells that release cytokines and recruit macrophages and other inflammatory cells. This leads to delayed and cell-mediated reactions, such as contact dermatitis, tuberculin reaction, or graft rejection.