HESI RN Dosage Calculation IV ( 56 Questions)
The healthcare provider prescribes cefazolin 800 mg IM every 6 hours. The available vial is labeled, "Cefazolin 1 gram," and the instructions for reconstitution state, "For IM use, add 2.5 mL sterile water for injection to provide a total volume of 3.0 mL." How many mL should the nurse administer? (Enter numerical value only. If rounding is required, round to the nearest tenth.)
Correct Answer: 2.4
Here's how to calculate the volume (mL) of the reconstituted cefazolin solution the nurse should administer for each dose:
1. We know the following:
Prescribed dose: 800 mg cefazolin (given)
Vial information:
Contains 1 gram cefazolin (given) = 1000 mg (since 1 gram = 1000 milligrams)
Reconstituted with 2.5 mL sterile water for injection (given)
Yields a total volume of 3.0 mL (given)
2. We need to find the concentration of cefazolin (mg/mL) in the reconstituted solution.
3. Then, we can find the volume (mL) to administer for the prescribed dose (800 mg) considering the concentration.
Steps:
a. Calculate the concentration after reconstitution:
Total volume after reconstitution = 3.0 mL (given)
Total amount of cefazolin after reconstitution = 1 gram (from the vial) = 1000 mg
Concentration (mg/mL) = Total amount of medication (mg) / Total volume after reconstitution (mL)
Concentration (mg/mL) = 1000 mg / 3.0 mL
Concentration (mg/mL) = 333.33 mg/mL (round to one decimal place)
b. Calculate the volume to administer:
Volume to administer (mL) = Dose (mg) / Concentration (mg/mL)
Volume to administer (mL) = 800 mg / 333.33 mg/mL
Volume to administer (mL) = 2.4 mL (round to nearest tenth)
Therefore, the nurse should administer approximately 2.4 mL of the reconstituted cefazolin solution intramuscularly every 6 hours.
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