When caring for a patient with angina, the nurse instructs the patient to place the nitroglycerin tablet between the cheek and the gums. Which route of administration is the nurse referring to?

A. Reye syndrome is correct because administering aspirin to children, especially during viral illnesses like the flu, can lead to this serious and potentially fatal condition characterized by acute encephalopathy and liver failure.

B. Excess antiplatelet action is incorrect; while aspirin does have antiplatelet effects, this is not the primary concern in a child with a viral illness.

C. Asthma is incorrect; while some individuals with asthma may have sensitivity to aspirin, it is not specifically related to the child's flulike illness.

D. Salicylate poisoning is incorrect; while high doses of aspirin can lead to toxicity, the immediate risk in the context of flu-like illness is Reye syndrome, which is a more specific concern.

A. Clients with hepatitis C experience liver impairment, which is crucial for drug metabolism; hence, they are likely to have impaired drug metabolism.

B. Treatment for basal cell skin cancer typically does not affect liver function significantly, so drug metabolism is less likely to be impaired.

C. Clients requiring dialysis have impaired renal function, affecting drug excretion more than metabolism, so they may not necessarily have impaired drug metabolism.

D. Dehydration following diarrhea can affect the body's overall function, but it is less directly related to impaired drug metabolism compared to liver dysfunction.