The nurse reviews laboratory results for a client with disseminated intravascular coagulation who is being monitored for complications related to abnormal clotting.
Which findings would most suggest the development of organ dysfunction secondary to thrombotic microangiopathy?
Decreased respiratory rate and normal oxygen saturation.
Elevated blood urea nitrogen (BUN) and serum creatinine.
Decreased white blood cell count and increased bilirubin.
Elevated liver transaminases and normal coagulation profiles.
The Correct Answer is B
Disseminated intravascular coagulation involves systemic activation of coagulation, leading to microthrombi formation. Assessing for organ dysfunction requires understanding how thrombotic microangiopathy causes ischemia in high-vascularity organs, specifically focusing on renal and hepatic biomarkers and physiological changes in perfusion.
Choice A rationale
Thrombotic microangiopathy in the lungs would typically cause increased respiratory rates and decreased oxygen saturation due to impaired gas exchange. Decreased rates and normal saturation do not indicate the ischemic damage associated with microvascular clotting.
Choice B rationale
The kidneys are highly susceptible to microthrombi. Elevated BUN (normal 10 to 20 mg/dL) and creatinine (normal 0.6 to 1.2 mg/dL) indicate acute kidney injury caused by fibrin deposition and subsequent ischemia in the glomerular capillaries.
Choice C rationale
While bilirubin might rise due to hemolysis, white blood cell counts are not a primary indicator of thrombotic organ dysfunction. Bilirubin increases are more common in hepatic failure or red blood cell fragmentation during DIC.
Choice D rationale
DIC typically presents with abnormal coagulation profiles, including prolonged PT and PTT and low fibrinogen. Normal profiles would contradict the diagnosis of DIC, even if transaminases were elevated due to localized hepatic microvascular occlusion.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Patient safety protocols require the application of fall prevention strategies and environmental management. Knowledge of hospital safety standards, mobility mechanics, and the legal implications of restraints is necessary to select interventions that minimize injury risks while maintaining a safe therapeutic environment.
Choice A rationale
Keeping the bed in the lowest position minimizes the vertical distance to the floor, significantly reducing the impact force and potential for injury if a client attempts to exit the bed unassisted. This is a primary fall prevention standard.
Choice B rationale
Dim lighting during daytime hours decreases visual acuity and increases the risk of environmental trips or missteps. Adequate illumination is required for clients to identify obstacles, perceive depth accurately, and navigate their surroundings safely during active hours.
Choice C rationale
Barefoot walking increases the risk of slipping on smooth hospital floor surfaces. Safety protocols mandate non-skid footwear or socks with rubber grips to provide necessary traction and stability, preventing falls related to a lack of foot-to-floor friction.
Choice D rationale
Raising all four side rails is classified as a physical restraint in many jurisdictions and can actually increase injury severity. Clients may attempt to climb over the rails, leading to falls from a much greater height.
Correct Answer is D
Explanation
Monitoring traumatic brain injury involves assessing neurological changes that indicate secondary brain injury. Knowledge of intracranial dynamics and Cushing's triad is essential to identify shifting brain tissue or worsening herniation, which requires immediate medical or surgical intervention to save life.
Choice A rationale
Pupillary changes indicate pressure on the oculomotor nerve but may occur earlier than profound neurological collapse. While important, they are often secondary indicators compared to the global decline seen in mental status and motor function.
Choice B rationale
Fever and elevated blood pressure can occur in brain injury due to hypothalamic dysfunction or sympathetic surges. However, without bradycardia and irregular respirations, they do not definitively indicate immediate, late-stage intracranial pressure emergencies.
Choice C rationale
Headache and nausea are subjective, early signs of increased intracranial pressure. While concerning and requiring monitoring, they do not signify the urgent physiological crisis or neurological deficit represented by a plummeting level of consciousness.
Choice D rationale
A decreased level of consciousness is the most sensitive indicator of neurological deterioration. Coupled with one-sided weakness, it suggests focal deficits or impending herniation, necessitating immediate reporting to prevent permanent brain damage or death.
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