The nurse is administering medications to a client who has severe liver damage. Which medications, as ordered below, will avoid the first pass effect? (SELECT ALL THAT APPLY)
Acetaminophen 500 mg PO q4h PRN headache
Dulcolax suppository one per rectum PRN
Aspirin 10 mg PO crush and put in apple sauce
Fentanyl 25 mcg/h via transdermal patch daily
Morphine 0:4 mg IV q4h PRN severe pain
Correct Answer : B,D,E
Choice A rationale: Acetaminophen 500 mg PO is subject to the first pass effect as it is absorbed through the gastrointestinal system.
Choice B rationale: Dulcolax suppository is not subject to the first pass effect as it is administered rectally.
Choice C rationale: Aspirin 10 mg PO is subject to the first pass effect as it is absorbed through the gastrointestinal system.
Choice D rationale: Fentanyl 25 mcg/h via transdermal patch avoids the first pass effect as it is absorbed through the skin.
Choice E rationale: Morphine 0.4 mg IV avoids the first pass effect as it is administered intravenously.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale: Applying an ice pack after a topical agent is not primarily for decreasing discomfort but rather to achieve a specific therapeutic effect.
Choice B rationale: Applying an ice pack can slow the absorption of the topical drug, allowing for prolonged local action.
Choice C rationale: Enhancing drug excretion is not typically achieved by applying an ice pack.
Choice D rationale: Maximizing drug distribution is not the primary purpose of applying an ice pack after a topical agent.
Correct Answer is A
Explanation
Choice A rationale: An inflammatory response, including mild fever and malaise, is common during the inflammatory phase of healing, which occurs in the initial postoperative period.
Choice B rationale: Proliferation is the phase of healing characterized by tissue repair and regeneration, not by fever and malaise.
Choice C rationale: Remodeling is the final phase of healing involving tissue maturation and strengthening, not associated with generalized body responses.
Choice D rationale: Infection is a separate complication and may present with more severe symptoms than mild fever and malaise.
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