Aron has been prescribed Lispro and among other medication. Such drugs act:

Choice A reason: Cirrhosis is a condition that affects the liver, not the kidneys. It is not related to nephropathy, which is kidney disease.

Choice B reason: Cardiac disease, while a common complication of diabetes, is not directly caused by nephropathy. Nephropathy primarily affects the kidneys and can lead to kidney failure, but it is not the leading cause of cardiac disease.

Choice C reason: Nephropathy in individuals with diabetes can lead to end-stage kidney disease (ESRD), also known as end-stage renal disease. This is a serious condition where the kidneys are no longer able to function adequately to maintain life, often requiring dialysis or a kidney transplant.

Choice D reason: Pulmonary disease affects the lungs and is not directly related to nephropathy. While diabetes can have complications that affect the lungs, nephropathy specifically targets the kidneys.

Choice A reason: Cushing's is not related to this type of edema. Cushing's syndrome is a condition caused by prolonged exposure to high levels of cortisol, a hormone produced by the adrenal glands. It can lead to various symptoms, including weight gain, thinning skin, and high blood pressure, but it does not describe the specific characteristic of edema that leaves an indentation when pressed.

Choice B reason: Swelling is a general term that describes an increase in the size of a body part, often due to the accumulation of fluid. While edema is a type of swelling, the term "swelling" itself does not specifically refer to the characteristic of leaving an indentation upon pressure.

Choice C reason: Dependent edema occurs in areas of the body that are lower than the heart, often due to gravity. This type of edema can be seen in conditions like heart failure or prolonged immobility. However, it does not specifically refer to the characteristic of pitting, which is the ability to leave an indentation upon applying pressure.

Choice D reason: Pitting edema is the correct term for this condition. It occurs when pressure is applied to a swollen area, forcing fluid movement and leaving a visible indentation that persists for some time. Pitting edema is commonly seen in conditions such as congestive heart failure, liver disease, and deep vein thrombosis. The extent and duration of the indentation can help assess the severity of the edema.