A nurse is caring for a client who has been taking sumatriptan for several months. Which of the following statements by the client indicates a therapeutic response to the medication?
"My hands are noticeably trembling less."
"My skin is no longer breaking out."
"My migraine headaches do not last nearly as long."
"My arthritis pain is not as severe as it was a few months ago."
The Correct Answer is C
Sumatriptan is a selective serotonin receptor agonist (triptan) that targets 5-HT1B and 5-HT1D receptors to cause cranial vasoconstriction. It effectively inhibits the release of pro-inflammatory neuropeptides and suppresses pain transmission within the trigeminal vascular system.
Rationale:
A. Reduction in hand tremors is not a therapeutic effect of sumatriptan, which is specific to migraine pathology. Tremors are usually managed with beta-blockers or dopaminergic agents. Sumatriptan does not influence the motor pathways of the central nervous system or the extrapyramidal system to decrease involuntary muscle movements or tremors in patients.
B. Improved skin condition or the reduction of acne breakouts is unrelated to the pharmacological action of sumatriptan. Triptans do not possess antimicrobial or hormonal properties that would affect the sebaceous glands or integumentary system. This statement would indicate a response to dermatological treatments rather than a medication used for acute migraine relief.
C. The statement that migraine headaches are shorter in duration indicates a therapeutic response, as sumatriptan is used for the acute treatment of migraine attacks. By stimulating serotonin receptors, it reverses the vasodilation and perivascular inflammation responsible for the throbbing pain. Success is measured by the rapid relief of pain and associated symptoms like photophobia.
D. Arthritis pain relief is not an effect of sumatriptan because it is not a general analgesic or anti-inflammatory agent like NSAIDs. Sumatriptan specifically targets receptors found in the cranial blood vessels and has no affinity for peripheral joints or musculoskeletal tissues. It would be ineffective in managing chronic joint inflammation or systemic arthritic pain.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Safe medical documentation requires the use of standardized terminologyand the avoidance of dangerous abbreviations to prevent medication errors. The Joint Commission maintains a "Do Not Use" list, which prohibits notations that are easily misinterpreted, such as trailing zeros or missing leading zeros.
Rationale:
A.This entry is incorrect because it uses the abbreviation "QD" for daily, which is on the prohibited list as it can be mistaken for "QID" (four times daily). Additionally, it fails to include the unit of measurement "mg" after the dosage, which is a critical safety component. Standardized documentation requires writing out the word "daily" and including full units to ensure there is no ambiguity in the medical record.
B.This is the correct entry because it follows all safety protocols, including the use of a leading zero (0.25 mg) and writing out "daily" and "by mouth." It also correctly documents that it was a verbal order (VO) and identifies both the prescribing provider and the receiving nurse. This level of detail ensures the order is legally sound and minimizes the risk of a ten-fold dosing error or route confusion.
C.This entry is unsafe because it lacks a leading zero (.25 mg), which could result in the patient receiving 25 mg instead of 0.25 mg if the decimal point is missed. Such a massive overdose of digoxin would likely be fatal due to its narrow therapeutic index and cardiac toxicity. Furthermore, it fails to document that the order was a verbal order, which is necessary for legal and clinical accountability.
D.Similar to choice C, this entry is incorrect due to the omission of the leading zero before the decimal point (.25 mg). While it correctly uses "VO" and "daily," the lack of a leading zero is a high-risk charting error that directly violates patient safety standards. Proper notation must always place a zero before a decimal to highlight the fractional nature of the dose to all clinical staff.
Correct Answer is C
Explanation
Warfarin is a Vitamin K antagonistthat interferes with the synthesis of clotting factors II, VII, IX, and X. It has a narrow therapeutic window and is subject to numerous cytochrome P450interactions with herbal supplements and foods. Maintaining a consistent intake of Vitamin K and avoiding platelet-inhibitingsubstances is vital to prevent hemorrhage or thromboembolic events.
Rationale:
A.Using a hard bristle toothbrush is incorrect because warfarin therapy increases the risk of gingival bleeding due to impaired coagulation. Clients are instructed to use a soft-bristle toothbrush to minimize trauma to the oral mucosa and prevent bleeding episodes. Any source of mechanical irritation can lead to significant hemorrhage in a patient who is therapeutically anticoagulated.
B.Getting an INR checked once a year is dangerously infrequent for a patient on warfarin therapy. The International Normalized Ratio (INR) must be monitored every few days when starting therapy and at least monthly once a stable dose is established. Frequent monitoring is necessary to adjust the dosage and ensure the patient stays within the therapeutic range of 2.0 to 3.0.
C.St. John's wort is a potent inducer of hepatic enzymes that significantly increases the metabolism of warfarin, leading to subtherapeutic levels. If the client takes this supplement, they are at a much higher risk of developing dangerous blood clots or suffering a stroke. Avoiding this herbal interaction indicates the client understands how to maintain the effectiveness of their anticoagulant.
D.Eating cantaloupe is generally safe for patients on warfarin as it does not contain high levels of Vitamin K that would interfere with the medication. The client should instead be taught to maintain a consistent intake of dark, leafy green vegetables like spinach or kale. Restricting fruits like cantaloupe is an unnecessary dietary limitation that does not affect the drug's efficacy.
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